Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia

A. Ju. Krivoruchko; V. A. Aksenenko; A. N. Kvochko; R. V. Pavlov

doi:10.17816/JOWD89483

Journal of obstetrics and women's diseases ›› 2000, Vol. 49 ›› Issue (4) : 82 -85. DOI: 10.17816/JOWD89483

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Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia

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Abstract

To determine the role of cytokines in pathogenesis of pre-eclampsia, production of IL1/3, IL4, IL6 and TNFa by chorionic villous explant of healthy women and patients with pre-eclampsia under the influence of hypoxia was investigated. The results received testify to considerable changes of cytokine production connected with the form of pre-eclampsia. So, placenta as a source of cytokines in case of pre-eclampsia appears to injure endothelium.

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cytokines / villous culture / chorion / late gestosis / hypoxia / placenta

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A. Ju. Krivoruchko, V. A. Aksenenko, A. N. Kvochko, R. V. Pavlov. Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia. Journal of obstetrics and women's diseases, 2000, 49(4): 82-85 DOI:10.17816/JOWD89483

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