Pathogenesis and diagnosis of autoimmune oophoritis
V. V. Potin , E. E. Smagina , A. M. Gzgzian , V. V. Rulev , T. G. Ioseliani
Journal of obstetrics and women's diseases ›› 2000, Vol. 49 ›› Issue (2) : 59 -66.
Pathogenesis and diagnosis of autoimmune oophoritis
A review of modem literature on problems of etiology, pathogenesis and diagnosis of ovarian autoimmune disorders is presented. Histologic and immunologic diagnostic methods are described. A comparison of our own and literary data allowed to substantiate the existence of normogonadotropic form of autoimmune oophoritis which is not accompanied by primordial follicles disorders and does not lead to the development of hypergonadotropic amenorrhea. This is confirmed by reliable differences in the occurrence of antigens of class IIHLA system in cases of normogonadotropic and hypergonadotropic forms of disease. Attention is attracted to the necessity of early diagnosis while of gonadotropins level is in the limits of physiological fluctuations.
autoimmune oophritis / normogonadotropic form / hypergonadotropic form / gonadotropins
Eсо-Vector
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