The first oocyte donor bank and "Oocyte Donorship" program realization
E. K. Ailamazyan , Yu. S. Verlinsky , E. V. Isakova , V. S. Korsak , T. N. Shlyahtenko
Journal of obstetrics and women's diseases ›› 2000, Vol. 49 ›› Issue (1) : 23 -27.
The first oocyte donor bank and "Oocyte Donorship" program realization
During three years (1996-99)266 women of the reproductive age addressed our Center expressing the wish to be oocyte donors. Äs a result of the 2-phase selection only 45 zvomen (20-33 years of age) were admitted into the “oocyte donors bank”. In order to study the reaction of ovaries for gonadotropic stimulation of healthy women with normal reproduction function we carried out the analyses of the results of superovulation in the group of 14 donors participating in the program for the first time.
The group of recipients consisted of 22 women (26-57years of age). The average age of the group zvas 39,2 years. For 15 patients it was the first experience of using donor’s oocytes in the frame of IVF program.
In order to define the factors affecting frequency rate of pregnancy development all recipients were split into 2 groups: 1st group was formed by the women with pregnancy developed, 2nd with pregnancy not developed. In the both groups most recipients (72%) suffered hypergonadotropic insufficiency of ovaries.
The“ Oocyte Donorship” program proves its high efficiency and allows providing 50% frequency rate of pregnancy development.
oocyte donors / donor bank / Oocyte Donation Program / superovulation / ovarian hyperstimulation
| [1] |
Abdala Н. I., Wren M.Е., Thomas A., Korea L. Age of the uterus does not affect pregnancy or implantation rates; a study of egg donation in women of different ages sharing oocytes from the same donor. Hum. Reprod., 1997, 76(4): 827-829. |
| [2] |
Buster J.E., Bustilo M. Non- surdical transfer of in vivo fertilaised donated ova to five infertile women: report of two pregnancies. Lancet, 2 (8343): 1983, 223-224. |
| [3] |
Can C.L., Devendra S. Oocyte and embryo donation. Ann Acad Med Singapore, 21 (4): 545-553, 1992. |
| [4] |
Guidelines for gamete and embryo donation. FertiI Steril, 70(4), supplements, p. 13. |
| [5] |
Gunning J. Oocyte donation: the legislative framework in Western Europe. Hum. Reprod., 71(1): 98- 102, 1998. |
| [6] |
Levran D., Ben-Shlomo I., Dor J., Ben - Rafael Z., Nebel L., Mashiach S. Aging of endometrium and oocytes: observations on conseption and abortion rates in an egg donation model. Fertil. Steril., 1991, 56(6): 1091-1094. |
| [7] |
Levran D., Goldstein I., Dor J., Mashiach S., BiderD. Parameters that influence the results of in vitro fertilization/embryo transfer: a study of an egg donation model. Gynecol Endocrinol., 10(6): 401-406, 1996. |
| [8] |
Ludic M. L., Liu J. H., Rebar R.W., Thomas M. A., Cedars M. I. Success of donor oocyte in vitro fertilization- embryo transfer in recipients with and without premature ovarian failure. Fertil. Steril., 9(1): 98-102, 1996. |
| [9] |
Michalas S. Lautradis D., Drakakis P, Kallianidis K., Milingos S., Deligeoroglou E., Aravantinos D.A flexible protocol for the induction of recipient endometrial cycles in an oocyte donation programme [see comments]. Hum. Reprod., 11 (5): 1063-1066, 1996. |
| [10] |
Remohri J., Gartner B., Gallardo E., YalilS., Simron C., Pel Heer A. Pregnancy and birth rates after oocyte donation. Fertil. Steril., 11 (40): 717-723,1997. |
| [11] |
Sauer M.V., Paulson R.J., Lobo R. A. Rare occurence of ovarian hyperstimulation syndrome in oocyte donors. Int. J. Gynecol. Obstet., 52, 1996, 259-262. |
| [12] |
Stolwijk A.M., Zielhuis G.A., Sauer M.V., Hamilton C.J., Paulson R.J. The impact of the womanysage on the success of standard and donor in vitro fertilization. Fertil. Steril., 67 (4): 702-710, 1997. |
| [13] |
Volarcik K., Sheean L., Goldfarb J., Woods L., Abdul-Karim F.W., Hunt P. The meiotic competence of in-vitro matured human oocytes is influenced by donor age: evidence that folliculogenesis us compromised in the reproductively aged ovary. Hum. Reprod., 13(1): 154-160, 1998. |
| [14] |
14: Volarcik K., Sheean L, Goldfarb J., Woods L., Abdul-Karim F. W., Hunt P. Oocyte donation program: pregnancy and implantation rates in women of different ages sharing oocytes from single donor. Fertil. Steril., 13(1): 94-97, 1996. |
| [15] |
Wong I.L., Legro R.S., Lindheim S.R., Paulson R.J., Sauer M.V. Efficacy of oocytes donated by older women in an oocyte donation programme. Hum. Reprod., 56(6): 820-823, 1996. |
| [16] |
Yaron Y., Ochshorn Y., Amit A., Kogosowski A., Yovel I., Lessing J.B. Oocyte donation in Israel: a study of 1001 initiated treatment cycles. Hum Reprod, 13(7): 1819-1824, 1998. |
| [17] |
Younis J.S., Mordel N., Lewin A., Schenker J.G., Läufer N. Artifideal endometrial preparation for oocyte donation: the effect of estrogen stimulation on clinical outcome. J Assist. Reprod. Genet., 9(4): 222- 227, 1992. |
Eсо-Vector
/
| 〈 |
|
〉 |