Environmental pollution, immunology researches, humoral immunity, immunological indices of risk, pregnant women, new-born, children of the first year of age
O. V. Sivochalova , L. A. Dujeva , G. V. Golovaneva
Journal of obstetrics and women's diseases ›› 2003, Vol. 52 ›› Issue (2) : 72 -76.
Environmental pollution, immunology researches, humoral immunity, immunological indices of risk, pregnant women, new-born, children of the first year of age
Pregnant women in last trimester of pregnancy living in 2 districts of Moscow were clinically examined. The immunology researches show that 69 % of all pregnant have the changes in humoral immunity: decrease of IgG, increase of IgM,CIC,and IgE.
It was also found that somatic health of women pregnancy complications and corresponding immunological changes found in last trimester of pregnancy negatively influenced on health of new-born and formation of health during first year of age. So diagnosis of intrauterine fetus hypoxia. Low Apgar score (6 points and lower), brain circulation disorders of hypoxia genesis diagnosis of hypertensional syndrome was significantly more frequent between new-born of ecologically polluted district.
The study conducted permitted to substantiate the immunological indices of risk for reproductive health of women and health of their offspring. These are: a) decrease of IgG concentration in blood, b) increase of CIC along with rise of overall IgE, c) presence of antihapten antibodies to environmental pollutants. These indices are recommended for inclusion in social and hygienic monitoring, ordinances of Health Ministry in the sphere of maternity and childhood protection.
pregnant women / immunology researches / environmental
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