Hormonal rehabilitation of patients with cervical cancer after radical surgical treatment
A. F. Urmancheeva , L. M. Bernstein , М. M. Бурмина , D. R. Zeldovich , V. B. Gamayunova , I. G. Kovalenko
Journal of obstetrics and women's diseases ›› 2001, Vol. 50 ›› Issue (1) : 18 -22.
Hormonal rehabilitation of patients with cervical cancer after radical surgical treatment
Radical surgical treatment with and without radiation often induces symptoms of premature menopause in cervical cancer (CC) patients. Few retrospective studies seem to suggest that hormonal replacement therapy (HRT) is not detrimental for patients with CC and can improve life quality in this group of women. To investigate the effect of HRT on menopausal symptoms inpatients with С C history, 85 patients after CC treatment, 22-51 years old, were included into this research. In 59 patients HRT was carried out to overcomepostovariectomic syndrome (POES). Severity of menopausal symptoms, serum estradiol, FSH and lipid profiles were evaluated. The research showed high therapeutic effect as to reducing the frequency of postovariectomic frustration in HRT application. No recurrences of CC were observed in this group of patients. HRT side effects were extremely rare. HRT can effectively cure climacteric symptoms in women with surgical menopause induced by CC treatment.
hormonal rehabilitation / treatment of malignant neoplasms / effectiveness of HRT
| [1] |
Алиханова З.М. Патофизиология системных изменений у женщин репродуктивного возраста после тотальной овариоэктомии // |
| [2] |
Акушерство и гинекология. - 1996. - №1. - С. 111-14. |
| [3] |
Чиссов В.И., Старинский В.В., Ковалев Б. Н., Мерабишвили В. М., Петрова Г.В., Александрова Л.М., Харченко Н.В, Филиппова Е.Р. Злокачественные опухоли в России: статистика, научные достижения, проблемы // Казанский медицинский журнал. - 2000. - №4. -С. 241-249. |
| [4] |
Adami Н.О., Persson I., Hoover R. et al. Risk of cancer in women receiving hormone replacement therapy //1 nt. J. Cancer. - 1989:44: 833-839. |
| [5] |
BurgerC.W., Koomen I., Peters N.A.Y.B., van Leewen F.E., Kenemans P. Postmenopausal hormone replacement and cancer of the female genital tract and the breast // Eur. Menopause J. 1997:4( 1): 23-36. |
| [6] |
Burger C.W., van Leewen F.E., Scheele F. et. al. Hormone replacement therapy in women treated for gynaecologic malignancy // Maturitas. 1999: 32: 69-76. |
| [7] |
Li C. et al. Quality of life in long-term survivors of cervical cancer // Maturitas. 1999. 32(2): 95-102. |
| [8] |
OnnisA., Marchetti M. Hormonal replacement therapy and gynecological cancer // Clin. Exp. Obstet. Gynecol. 1999: 26(1): 5-8. |
| [9] |
Parazzini F. et al. Case-control study of oestrogen replacement therapy and risk of cervical cancer// Br. Med. J. 1997:315:85-88. |
| [10] |
Ploch E. Hormone replacement therapy in patients after cervical cancer treatment // Gynecol. Oncol. 1987:26:169-177. |
Eсо-Vector
/
| 〈 |
|
〉 |
PDF
