Donors of nitric oxide in the treatment of preeclampsia: influence on the state of the endothelium and hemodynamics in the functional mother-placenta-fetus system
Elena A. Malakhovskaya , Marina S. Zainulina
Journal of obstetrics and women's diseases ›› 2004, Vol. 53 ›› Issue (4) : 42 -45.
Donors of nitric oxide in the treatment of preeclampsia: influence on the state of the endothelium and hemodynamics in the functional mother-placenta-fetus system
We investigated influence of nitrovasodilators on functional status of endothelium in preeclampsia with measuring of thrombomodulin, sICAM-1 and sVCAM-1 plasma levels. Changes in feto-placental and uteroplacental hemodynamics were analysed after treatment with isosorbide mononitrate and isosorbide dinitrate. Our results showed efficacy of nitric oxide donors in complex therapy of preeclampsia.
nitric oxide donors / therapy of gestosis / endothelium / hemodynamics in the functional mother-placenta-fetus system
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