On the pathogenetic mechanisms of premature detachment of the normally located placenta

Marina S. Zainulina

Journal of obstetrics and women's diseases ›› 2004, Vol. 53 ›› Issue (4) : 19 -25.

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Journal of obstetrics and women's diseases ›› 2004, Vol. 53 ›› Issue (4) : 19 -25. DOI: 10.17816/JOWD88614
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On the pathogenetic mechanisms of premature detachment of the normally located placenta

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Abstract

The aim of this study was to study the systemic and regional mechanisms of endothelial dysfunction and thrombophilia in the pathogenesis of premature detachment of the normally located placenta.

To fulfill the assigned tasks, 340 women were examined. The main group included 72 women with premature detachment of the normally located placenta. The comparison groups consisted of 81 pregnant women in the III trimester of physiological pregnancy and 187 pregnant women in the III trimester with preeclampsia of varying severity.

Keywords

pathogenetic mechanisms / premature placental abruption / placenta / preeclampsia / a risk factor for placental abruption / hypertension / polymorphism

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Marina S. Zainulina. On the pathogenetic mechanisms of premature detachment of the normally located placenta. Journal of obstetrics and women's diseases, 2004, 53(4): 19-25 DOI:10.17816/JOWD88614

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References

[1]

Айламазян Э.К., Зайнулина М.С., Петрищев Н.Н. К вопросу о маркерах повреждения сосудистой стенки при позднем гестозе // Журн. акуш. и женск. бол. — 1998. - Вып. 1. - С. 19-23.

[2]

Зайнулина М.С., Петрищев Н.Н. Эндотелиальная дисфункция и ее маркеры при гестозе // Журн. акуш. и женск. бол. - 1997,- Вып. 1. - С. 59_б2.

[3]

Милованов А.П. Патология системы: мать-плацента-плод.: Руководство для врачей. - М.: Медицина, 1999. - 448 с.

[4]

Серов В.Н., Макацария А.Д. Тромботические и геморрагические осложнения в акушерстве. — М.: Медицина, 1987. — 288 с.

[5]

Шехтман М.М. Руководство по экстрагенитальной патологии у беременных. - М.: Триада, 1999. - 816 с.

[6]

Brosens Renaer М. On the pathogenesis of placental infarcts in pre-eclampsia // J. Obstet. Gynaecol. Br. Commonw, Sep.1972, 79(9). - P. 794-9.

[7]

Brosens J.J., Pijnenborg R., Brosens I.A. The myometrial junctional zone spiral arteries in normal and abnormal pregnancies // Am. J. Obstet. Gynecol. - 2002, 187(5).

[8]

Chichakli L.O., Atrash H.K., Mac Kay A.P., Musani A.S., Berg C.J. Pregnancy-related mortality in the United States due to hemorrhage: 1979-1992. Obstet. Gynaecol. - 1999, 94(5 Pt 1). - P. 721 - 5.

[9]

Cockell A.P., Learmont J.G., Smarason A.K., Redman С. W., Sargent I.L., Poston L. Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial function // Br. J. Obstet. Gynaecol. - 1997, Feb., 104(2). - P. 235-40.

[10]

Jurgens H., Lindemann G., Raber G. Precocious loosening of placenta and infant mortality / Zentralbl. Gynakol., 1974, Jun. 21, 96(25). - P. 785-92.

[11]

Franchi E., Bigussi E., Cetin I., Facchetti E., Radaelli T., Bozzo M., Pardi G., Faioni E. M. Mutations in thetrombomodulin and the endothelial protein C receptor genes in the women with lat loss // British Journal of Haemotology. - 2001. - 01-Sep., 114(3). - P. 641-6.

[12]

Khong T.Y., Sawyer I.H., Heryet A.R. // An immunohistologic study of endothelialization of uteroplacental vessels in human pregnancy - evidence that endothelium is focally disrupted by tromboplast in preeclampsia. Am. J. Obstet. Gynaecol. - 1992. - Sep., 167930. - P. 751-6.

[13]

Knight M., Redman C. W., Linton E.A., Sargent I.L. Shedding of syncytiotrophoblast microvilli into the maternal circulation in preeclamptic pregnancies // Br. J. Obstet. Gynaecol. - 1998, Jun., 105(6). - P. 632-40.

[14]

Krikun G., Lockwood C.J., Wu X.X., Zhou X.D., Guller S., Calandri C., Guha A., Nemerson Y., Rand J.H. The expression of the placental anticoagulant protein, annexin V, by villous trophoblasts. Immunolocalization and in vitro regulation. Placenta 1994; 15: 601-12.

[15]

Labarrere C.A., Faulk W.P. Antigenic identification of cells in spiral artery trophoblasti invasion: validation of histologic studies by triple-antibody immunocytochemistry // Am. J. Obstet. Gynaecol. - 1994. - Jul., 171(1). - P. 165-171.

[16]

Nishida H., Masamichi S., Kurechi K., Asada A., Kubo S., Funakawa H. Fetal growth curve of Japanese. Acta Neonat Jpn ,1984; 20: 90-97.

[17]

Rand J.H., Wu XX., Andree H.A., lockwood C.J., Guller S., Scher J., Harpel P.C. Pregnancy loss in the antiphospholipid-antibody syndrome — a possible thrombogenic mechanism // N. Engl. J. Med. - 1997, Jul., 17, 337(3). P. 154-60.

[18]

Rand J.H., Wu X.X., Guller S., Gil J., Guha A., Scher G, Lockwood C.J. Reduction of annexin V (placental anticoagulant protein-1) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion // Am. J. Obstet. Gynecol. - 1994, Dec., 171(6). - P. 1566-72.

[19]

Rand J.H., Wu X., Guller S., Scher J. Antiphospholipid immunoglobulin G antibodies reduce annexin V levels on syncytiotrophoblasts apical membranes and in culture media of placental villi // Am. J. Obstet. Gynecol. - 1997, Oct., 177(4). - P. 918-23.

[20]

Rand J.H., Wu X.X., Guller S., Gil J., Guha A., Scher J., Lockwood C.J. Reduction of annexin V (placental anticoagulant protein) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion // Am J. Obstet Gynecol. - 1994; 171:1566-1572.

[21]

Rutherford R.A., McCarthy A., Sullivan M H., Elder M.J., Polak J.M., Wharton J. Nitric oxide synthase in human placenta and umbilical cord from normal, intrauterine growth-related and preeclamptic pregnancies // Br. J. Pharmacol. - 1995, Dec., 116(8). - P. 3099-109.

[22]

Sato Y. Distribution and motion of calphobindin in the human body. Acta Obstet Gynaecol Jpn . - 1991, 43:65-72.

[23]

Sheppard B.L., Bonnar J. Uteroplacental hemostasis in intrauterine fetal growth retardation. Semin. Thromb. Hemost. - 1999, 25(5). - P. 443-6.

[24]

Verspyck E., Le Cam-Duchez V., Borg J.Y, Marpeau L. Inherited thrombophilia and pregnancy // J. Gynaecol. Obstet. Biol. Reprod. (Paris). -2000, May, 29(3). - P. 227-9.

[25]

Wang X., Campos B., Kaetzel M.A., Dedman J.R. Secretion of annexin V from cultered cells requires a signal peptide. Placenta. - 2001, Nov., 22(10). - P. 837-45.

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