Role of bio-genic amines for the hypothalamic regulation of reproductive function

Abstract

• The present review is dedicated to monoaminergic systems involved in hypothalamic regulation of reproduction, as well as to the role of the systems in GnRH synthesis and secretion regulation. Data are presented on the ovarian steroid hormones, the suprachiasmatic nuclei of the hypothalamus, in which the central oscillator of a mammalian organism's diurnal rhythms is located, and on the pineal hormone melatonin involved in formation of reproductive cycles. Both own results and literature data referring to the role of diurnal rhythms of the activity of monoaminergic systems of the hypothalamus in the central regulation of reproduction are discussed.

Keywords

biogenic amines / hypothalamus / diurnal rhythms / suprachiasmatic nuclei / melatonin / reproductive cycles

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