Etiо pathogenesis of spontaneous abortion
О. N. Arganova , N. G. Kosheleva
Journal of obstetrics and women's diseases ›› 2004, Vol. 53 ›› Issue (1) : 37 -41.
Etiо pathogenesis of spontaneous abortion
One studied immunologic and genetic aspects of spontaneous abortion and the placenta insufficiency role in this pathology. It was determined, that increasing the production of cytokines by placenta's macrophages through something leads to increasing the reduced myometrium activity. Under cariotyping husbands and wives had spontaneous abortions on early terms it was found various genic and endocrine disturbtions. Modern topic diagnostics and algorithm of pregnancy observation with consideration of spontaneous abortion etiopathogenesis, treatment and placenta insufficiency prophylactics have permitted in most cases (more 93%) to give normal term of birth, to decrease perinatal losses.
pregnancy / spontaneous abortion / predisposition genes / placenta's insufficiency / macrophages / aggregation of thrombocytes
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