Bone mineral density and risk factors of osteoporosis in premenopausal Saint Petersburg women's

Abstract

In article outcomes of a research of 96 premenopausal women with continuous menstrual cycle and any diseases. BMD screened for all patients in hip, vertebrals and arm by DEXA Hologic QDR 4500 Elite. Osteopenia reveled in 41,7% women in lumbal spine. The main risk factors of low BMD are: low level of progesterone, anovulation, slow physical activity, low weight.

Keywords

osteopenia / premenopause / bone mineral density / risk factors for osteoporosis

References

[1] Arlot М.Е., Sornay-Rendu Е., Garnero Р. et al. Apparent pre and postmenopausal bone loss evaluated by DXA at different skeletal sites in women: The OFELY cohort // J. Bone Miner. Res. - 1997. - Vol. 12. - P. 683-690.

[2] Blum M. Wiegth and body mass index at menarche are associated with premanopausal bone mass // Osteoporosis. - 2001. - Vol. 12, N 7. - P. 588-594.

[3] Blum M., Harris S.S. et al. Weight and body mass index at menarche are associated with premenopausal bone mass // Osteoporosis Int. — 2001. - Vol. 12, Suppl. 7. — P. 588-594.

[4] Burger H, de Laet C.E., Van Daele P.L. et al. Risk factors for increased bone loss in an elderly population: the Rotterdam Study // Am. J. Epidemiol. - 1998. - Vol. 147. - P. 871-879.

[5] Carter D.R., Bouxsein M.L., Marcus R. New approaches for interpreting projected bone densitometry data // J. Bone Miner. Res. - 1992. - Vol. 7. - P. 137-145.

[6] Christiansen C., Riis B.J. Beta-estradiol and continuous norethisterone: a unique treatment for established osteoporosis in elderly women // J. Clin. Endocrinol. Metab. - 1990. - Vol. 71. - P. 836-841.

[7] Citron J.T., Ettinger B., Genant H.K. Spinal bone mineral loss in estrogenreplete, calcium-replete premenopausal women // Osteoporos Int. - 1995. - Vol. 5. - P. 228-233.

[8] Diaz C.M., Carrasco de la Pena J.L., Honorato P.J. et al. Study of bone mineral density in lumbar and femoral neck in a Spanish population. Multicentre Research Project on Osteoporosis // Osteoporos Int. - 1997. - Vol. 7. - P. 59-64.

[9] Eastell R., Yergey A.L. et al. Interrelationship among vitamin- D metabolism, true calcium-absorption, parathyroid function, and age in women: evidence of age-related intestinal resistance to 1,25-dihydroxyvitamin D action // J. Bone Miner. Res. — 1991. — Vol. 6. — P. 125-132.

[10] Ebeling P.R., Sandgren M.E. et al. Evidence of age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25 dihydroxyvitamin D, and intestinal vitamin D receptor concentrations in normal women // J. Clin. Endocrinol. Metab. — 1992. — Vol. 75. — P. 176-182.

[11] Fox K.M., Magaziner J., Sherwin R. et al. Reproductive correlates of bone mass in elderly women //J. Bone Miner. Res. - 1993. - Vol. 8. - P. 901-908.

[12] Fujiwara S., Fukunaga M., Nakamura T. et al. Rates of change in spinal bone density among Japanese women // Calcif. Tissue Int. - 1998. - Vol. 63. - P. 202-207.

[13] Haapasalo H., Kannus P., Sievanen H. et al. Development of mass, density, and estimated mechanical characteristics of bones in Caucasian females // J. Bone Miner. Res. - 1996. - Vol. 11. - P. 1751-1760.

[14] Hannan M.T., Felson D.T., Dawson-Hughes B. et al. Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study // J. Bone Miner. Res. - 2000. - Vol. 15. - P. 710-721.

[15] Harvey R.D., McFlardy K.C. et al. Measurement of bone collagen degradation in hyperparathyroidism and during thyroxine replacement therapy using pyridinium cross-links as specific urinary markers // J. Clin. Endocrinol. Metab. — 1991.-Vol. 72. - P. 1189-1194.

[16] Hui S.L., Perkins A.J., Zhou L. et al. Bone loss at the femoral neck in premenopausal white women: effects of weight change and sex-hormone levels // J. of Clin. Endocrinol. And Methabolism. - 2002. - Vol. 87. - P. 1539-1543.

[17] Hui S.L., Zhou L., Evans R. etal. Rates of growth and loss of bone mineral in the spine and femoral neck in white females // Osteoporos Int. - 1999. - Vol. 9. - P. 200-205.

[18] Kanders В., Dempster D.W., Lindsay R. Interaction of calcium nutrition and physical activity on bone mass in young women // J. Bone Miner. Res. - 1988. - Vol. 3. - P. 145- 149.

[19] Laitinen K., Valimaki M., Keto P. Bone mineral density measured by dual-energy x-ray absorptiometry in healthy Finnish women // Calcif. Tissue Int. - 1991. — Vol. 48. — P. 224-231.

[20] Lau K.W., Wang S.P. et al. Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption // J. Bone Miner. Res. - 1994. - Vol. 9. - P. 695-703.

[21] Leslie A., Siyka, Wesley P. et al. Hormonal determinants and disorders of peak bone mass in children // J. of Clin. Endocrinol. and Metabolism. - 2000. - Vol. 85, N 11. - P. 3951-3974.

[22] Liang C.T., Barnes J., Takamato 5., Sacktor B. Effect of age on calcium-uptake in isolated duodenum cells: role of 1,25- dihydroxyvitamin D3 // Endocrinology. — 1989. — Vol. 124. — P. 2830-2836.

[23] Manzoni P., Brambilla P. et al. Influence of body composition on bone mineral content in children and adolescends // Am. J. Clin. Nutr. - 1994. - Vol. 64. - P. 603-607.

[24] Matkovic V., Jelic T., Wardlaw G.M. et al. Timing of peak bone mass in Caucasian females and its implication for the prevention ofosteoporosis: inference from a cross-sectional model // J. Clin. Invest. - 1994. - Vol. 93. - P.799-808.

[25] Mazess R.B., Barden H. Bone density of the spine and femur in adult white females // Calcif. Tissue Int. - 1998. -Vol. 65. - P. 91-99.

[26] Morrison N.A., Qi J.C. et al. Prediction of bone density from vitamin D receptor alleles // Nature. — 1994. — Vol. 367. — P. 284-287.

[27] Nilas L., Christiansen C. Rates of bone loss in normal women: evidence of accelerated trabecular bone loss after the menopause // Eur. J. Clin. Invest. - 1988. - Vol. 18. -P. 529-534.

[28] Pantazi H., Papapetrou P.D. Changes in Parameters of bone and mineral metabolism during therapy for hyperthyroidism // J. Clin. Endocrinol. and Metabolism. - 2000 - Vol. 85, N 3. - P. 1099-1110.

[29] Peerenboom H., Keck E., Kruskemper H.L., Strohmeyer G. The defect of intestinal calcium transport in hyperthypoidism and its response to therapy // J. Clin. Endocrinol. Metab. - 1984. - Vol. 59. - P. 936-940.

[30] Prior J.C., Vigna Y.M., Schechter M.T., Burgess A.E. Spinal bone loss and ovulatory disturbances // N. Engl. J. Med. - 1990. - Vol. 323. - P. 1221-1227.

[31] Recker R.R., Lappe J.M., Davies K.M., Kimmel D.B. Change in bone mass immediately before menopause // J. Bone Miner. Res. - 1992. - Vol. 7. - P. 857-862.

[32] Riis B.J., Christiansen C., Johansen J.S., Jacobson J. Is it possible to prevent the bone loss in young women treated with LH-RH agonists // J.Clin. Endocrinol. Metab. — 1990. - Vol. 70. - P. 920-924.

[33] Seeman E. From density to structure: growing up and growing old on the surfaces of bone // J. Bone Miner. Res. - 1997. - Vol. 12. - P. 509-521.

[34] Shrier D.K., Burman K.D. Subclinical hyperthyroidism: controversies in management // Am. Fam. Physician. - 2002. - Vol. 65, Suppl. 3. - P. 431-438.

[35] Siu L.H., Perkins A.J. et al. Bone loss at the femoral neck in premanopausal white women: effect of weight change and sex hormone levels // J. of Clin. Endocrinol. and Metabolism. - 2002. - Vol. 87, N 4. - P. 1539-1550.

[36] Snow-Harter C., Bouxsein M.L. et al. Effects of resistance and endurance exercise on bone mineral status of young women: a randomized exercise intervention trial // J. Bone Miner. Res. - 1992. - Vol. 7. - P. 761-769.

[37] Sowers M., Crutchfield M., Bandekar R. et al. Bone mineral density and its change in pre- and perimenopausal white women: The Michigan Bone Health Study // J. Bone Miner. Res. - 1998. - Vol. 13. - P. 1134-1140.

[38] Takamoto S., Seino Y., Sacktor B., Liang C.T. Effect of age on duodenal 1,25-dihydroxyvitamin D-3 receptors in Wistar rats // Biochim. Biophys. Acta. 0151 1990. — Vol. 1034. - P. 22-28.

[39] Tylavsky F.A., Anderson J.J.B. et al. Are calcium intakes and physical activity patterns during adolescence related to radial bone mass of white college-age females? // Osteoporosis Int. - 1992. - Vol. 2. - P. 232-240.

[40] World Health Organization Technical Report Series # 843: Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. — Jeneva, 1994.

[41] Yasuro K., Masaaki I. et al. Persistent increase in bone turnover in grades' patients with subclinical hyperthyroidism // J. of Clin. Endocrinol. Metab. - 2000. - Vol. 85, N 11.

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