Morphological substantiation of pathogenetic therapyof external genital endometriosis
Irina V Markar’yan , Natalia V Yermolova , Nina A Drukker , Vladimir Y Mazhugin , Alexander N Rymasheuski , Sofia A Trushina
Journal of obstetrics and women's diseases ›› 2016, Vol. 65 ›› Issue (6) : 100 -103.
Morphological substantiation of pathogenetic therapyof external genital endometriosis
With the help of morphological study examined endometrioid heterotopias and eutopic endometrium in external genital endometriosis. Histological examination of surgical specimens of endometrial cancer were detected in endometrioid heterotopia, in eutopic endometrium occurred glandular-cystic hyperplasia of the proliferative and secretory type. Have been identified in the heterotopias expressed angiomatosis in patients with III-IV stages of endometriosis. It is proved that inflammatory changes in endometrioid heterotopias more pronounced with stage I-II stages of endometriosis, whereas hyalinosis sclerosis and how the outcomes of the process prevalent in patients with stage III-IV. The difference parameters in ectopic and eutopic endometrium shows marked morphological heterogeneity of both nuclear and cytoplasmic structures. Morphological changes in the heterotopias are intended to justify Dienogest (2 mg) for the treatment of external genital endometriosis.
external genital endometriosis / endometrioid heterotopia and atopiceski endometrium / morphological study
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Markar’yan I.V., Yermolova N.V., Drukker N.A., Mazhugin V.Y., Rymasheuski A.N., Trushina S.A.
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