Clinical and diagnostic criteria of cholestatic hepatosis severity in pregnancy
Natal’ya Vladimirovna Zhestkova , Valeriy Grigor’yevich Radchenko , Zhanna Nikolaevna Tumasova
Journal of obstetrics and women's diseases ›› 2015, Vol. 64 ›› Issue (2) : 25 -32.
Clinical and diagnostic criteria of cholestatic hepatosis severity in pregnancy
The function condition of hepatobiliar system was investigaited in 120 pregnant with cholestatic hepatosis. The main criteria of cholestatic hepatosis severity were skin itching accompanied with increasing of biliar acids levels, transaminazes activities, alkaline phosphatase and cholesterol levels. Based on clinical and laboratory dates the outcomes of pregnancy and delivery were analysed. There were revealed that pregnancy loss, gestosis, placental insufficiency, IUGR and fetal hypoxia were met more often in groups with middle- and high severe cholestatic hepatosis.
cholestasis / hepatosis / biliar acids / pregnancy
Zhestkova N.V., Radchenko V.G., Tumasova Z.N.
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