Towards the modern theory of parturition

Abstract

A system analysis of the results of modern scientific research has shown the most complex organization of the parturition, during which the unfolding and activation of the genetic birth program initially embedded in the mother and child occurs. 2–3 weeks before birth, desympatization and formation of an acupuncture network begin in the uterus. Along these acupuncture channels the wave flows of biologically active substances with both contractile and inhibitory properties move. These substances are delivered to the uterus by the bloodstream and blood cells. Some of them also have psychotropic properties, thereby enhancing the effect on the brain and causing a state of altered consciousness in the woman and her child. As labor approaches, the prenate revealed activation of the locus on chromosome 2, which allowed the researchers to assert that the prenate is initiator of the birth beginning. The totality of the data presented in the article served as a prerequisite for the formulation of a scientifically substantiated Theory of the parturition, according to which childbirth is a genetic-psychosomatic phenomenon, free of pain.

Keywords

parturition elements / nervous and acupuncture regulation / mother and child gene systems

References

[1] Cunningham FG, Leveno KJ, Bloom SL, et al. Williams obstetrics. 23rd edition. New York, Toronto: Medical Publishing Division; 2010. 1404 p.

[2] Cunningham F.G., Leveno K.J., Bloom S.L., et al. Williams obstetrics. 23rd edition. New York, Toronto: Medical Publishing Division, 2010. 1404 p.

[3] Podtetenev AD. Prediction, prevention and treatment of weakness and incoordination of labor: abstract of thesis [dissertation abstract]. Saint Petersburg; 2003. 37 p. (In Russ.)

[4] Подтетенев А.Д. Прогнозирование, профилактика и лечение слабости и дискоординации родовой деятельности: автореф. дис. … док. мед. наук. Санкт Петербург, 2003. 37 с.

[5] Sidorova IS. Physiology and pathology of labor. Moscow: MEDpress; 2000. 235 p. (In Russ.) EDN: QLNNXD

[6] Сидорова И.С. Физиология и патология родовой деятельности. Москва, МЕДпресс, 2000. 235 c. EDN: QLNNXD

[7] Kozonov GR, Kuzminykh TU, Tolibova GH, et al. Clinical course of childbirth and pathomorphological features of the myometrium in discoordinated labor activity. Journal of Obstetrics and Women’s Diseases. 2015;64(4):39–48. EDN: UVJNFL doi: 10.17816/JOWD64439-48

[8] Козонов Г.Р., Кузьминых Т.У., Толибова Г.Х., и др. Клиническое течение родов и патоморфологические особенности миометрия при дискоординированной родовой деятельности // Журнал акушерства и женских болезней. 2015. Т. 64, № 4. С. 39–48. EDN: UVJNFL doi: 10.17816/JOWD64439-48

[9] Aylamazyan EK, Serova VN, Radzinsky VE, et al. Obstetrics: national guide. Moscow: GEOTAR-Media; 2009. 1200 p. (In Russ.)

[10] Акушерство: национальное руководство / под ред. Э.К. Айламазян, В.Н. Серова, В.Е. Радзинского, и др. Москва: ГЭОТАР-Медиа, 2009. 1200 с.

[11] Baev OR, Belousova VS. Labor anomalies in primiparas over the age of 30. Problems of Gynecology, Obstetrics and Perinatology. 2005;4(1):5–10. EDN: IBLVTT

[12] Баев О.Р., Белоусова В.С. Аномалии родовой деятельности у первородящих женщин старше 30 лет // Вопросы гинекологии, акушерства и перинатологии. 2005. Т. 4, № 1. С. 5–10. EDN: IBLVTT

[13] Cunningham FG, Leveno KJ, Bloom SL, et al. Williams obstetrics. 24th edition. New York, Toronto: McGRAW-Hill; 2015.1377 p. (In Russ.)

[14] Cunningham F.G., Leveno K.J., Bloom S.L., et al. Williams obstetrics. 24th edition. New York, Toronto: McGRAW-Hill, 2015.1377 p.

[15] Aylamazyan EK. Obstetrics: a textbook for medical universities. 5th ed. Saint Petersburg: SpetsLit; 2005. 527 p. (In Russ.) EDN: QLMDED

[16] Айламазян Э.К. Акушерство: учебник для медвузов. 5-е изд. Санкт Петербург: СпецЛит, 2005. 527 с. EDN: QLMDED

[17] Persianinov LS, editor. Guide to obstetrics and gynecology. Moscow: Medgiz; 1963. Vol. 2, Book 2. (In Russ.)

[18] Руководство по акушерству и гинекологии / под ред. Л.С. Персианинова. Москва: Медгиз, 1963. Т. 2, Кн. 2.

[19] Jordania IF. Anatomy of the female genital organs. In: Persianinov LS, eds. Multi-volume guide to obstetrics and gynecology. Moscow: Medgiz; 1961. Vol. 1. P. 215–310. (In Russ.)

[20] Жорданиа И.Ф. Анатомия половых органов женщины. В кн.: Многотомное руководство по акушерству и гинекологии / под ред. Л.С. Персианинова. Москва: Медгиз, 1961. Т. 1. С. 215–310.

[21] Naidich MS. On the issue of topography and morphology of nerve elements in a woman’s uterus. Gynecology and obstetrics. 1929;(4):443–459. (In Russ.)

[22] Найдич М.С. К вопросу о топографии и морфологии нервных элементов в матке женщины. // Гинекология и акушерство. 1929. № 4. С. 443–459.

[23] Baksheev NS, Agarkov GB, Mikhailenko ET. Intramural innervation of the uterine muscle in women at different stages of pregnancy. Obstetrics and Gynecology. 1968;(3):3–7. (In Russ.)

[24] Бакшеев Н.С., Агарков Г.Б., Михайленко Е.Т. Интрамуральная иннервация мышцы матки у женщин на разных сроках беременности. // Акушерство и гинекология, 1968. № 3. С. 3–7.

[25] Shalyapina VG, Rakitskaya VV, Abramchenko VV. Adrenergic innervation of the uterus. Leningrad: Nauka; 1988. 50 p. (In Russ.)

[26] Шаляпина В.Г., Ракицкая В.В., Абрамченко В.В. Адренергическая иннервация матки. Ленинград: Наука, 1988. 50 с.

[27] Rakitskaya VV, Chudinov YuV, Shalyapina VG. Adrenergic innervation of the rat uterus outside and during pregnancy. Physiological Journal of the USSR named after I.M. Sechenov. 1990;76(9):1251–1259. (In Russ.)

[28] Ракицкая В.В., Чудинов Ю.В., Шаляпина В.Г. Адренергическая иннервация матки крыс вне и во время беременности // Физиологический журнал СССР имени И.М. Сеченова. 1990. Т. 76, № 9. С. 1251–1259.

[29] Winkler M, Kemp B, Classen-Linke I, et al. Estrogen receptor alpha and progesterone receptor A and B concentration and localization in the lower uterine segment in term parturition. J Soc Gynecol Investig. 2002;9(4):226–232.

[30] Winkler M, Kemp B, Classen-Linke I, et al. Estrogen receptor alpha and progesterone receptor A and B concentration and localization in the lower uterine segment in term parturition // J Soc Gynecol Investig. 2002. Vol 9, N 4. P. 226–232.

[31] Tabb TL, Thilander G, Grover A, et al. An immunochemical and immunocytologic study of the increase in myometrial gap junctions (and connexin 43) in rats and humans during pregnancy. Am J Obstet Gynecol. 1992;167(2):559–567.

[32] Tabb T.L, Thilander G., Grover A., et al. An immunochemical and immunocytologic study of the increase in myometrial gap junctions (and connexin 43) in rats and humans during pregnancy // Am J Obstet Gynecol. 1992. Vol. 167, N 2. P. 559–567.

[33] Nagatsu T. Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology. Essays Biochem. 1995;30:15–35.

[34] Nagatsu T. Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology // Essays Biochem. 1995. Vol. 30. P. 15–35.

[35] Savitsky GA. Biomechanics of cervical dilatation during childbirth. Saint Petersburg: ELBI; 1999. 116 p. (In Russ.)

[36] Савицкий Г.А. Биомеханика раскрытия шейки матки в родах. Санкт-Петербург: ЭЛБИ, 1999. 116 с.

[37] Bengtsson LP. Experiments on the control of myometrial activity in the non-pregnant woman. Postgrad Med J. 1969;45(519):73–74. doi: 10.1136/pgmj.45.519.73

[38] Bengtsson L.P. Experiments on the control of myometrial activity in the non-pregnant woman // Postgrad Med J. 1969. Vol. 45, N 519. P. 73–74. doi: 10.1136/pgmj.45.519.73

[39] Manabe Y, Sakaguchi M, Mori T. Distention of the uterus activates its multiple pacemakers and induces their coordination. Gynecol Obstet Invest. 1994;38(3):163–168. doi: 10.1159/000292471

[40] Manabe Y., Sakaguchi M., Mori T. Distention of the uterus activates its multiple pacemakers and induces their coordination // Gynecol Obstet Invest. 1994; Vol. 38, N 3. P. 163–168. doi: 10.1159/000292471

[41] Chan WY, Berezin I, Daniel EE. Effects of inhibition of prostaglandin synthesis on uterine oxytocin receptor concentration and myometrial gap junction density in parturient rats. Biol Reprod. 1988;39(5):1117–1128. doi: 10.1095/biolreprod39.5.1117

[42] Chan W.Y., Berezin I., Daniel E.E. Effects of inhibition of prostaglandin synthesis on uterine oxytocin receptor concentration and myometrial gap junction density in parturient rats // Biol Reprod. 1988, Vol. 39, N 5. P. 1117–1128. doi: 10.1095/biolreprod39.5.1117

[43] Chow L, Lye SJ. Expression of the gap junction protein connexin-43 is increased in the human myometrium toward term and with the onset of labor. Am J Obstet Gynecol. 1994;170(3):788–795. doi: 10.1016/s0002-9378(94)70284-5

[44] Chow L., Lye S.J. Expression of the gap junction protein connexin-43 is increased in the human myometrium toward term and with the onset of labor // Am J Obstet Gynecol. 1994. Vol. 170, N 3. P. 788–795. doi: 10.1016/s0002-9378(94)70284-5

[45] Garfield RE, Merrett D, Grover AK. Gap junction formation and regulation in myometrium. Am J Physiol. 1980;239(5):217–228. doi: 10.1152/ajpcell.1980.239.5.C217

[46] Garfield R.E., Merrett D., Grover A.K. Gap junction formation and regulation in myometrium // Am J Physiol. 1980. Vol. 239, N 5. P. 217–228. doi: 10.1152/ajpcell.1980.239.5.C217

[47] Sáez JC, Contreras JE, Bukauskas FF, et al. Gap junction hemichannels in astrocytes of the CNS. Acta Physiol Scand. 2003;179(1):9–22. doi: 10.1046/j.1365-201X.2003.01196.x

[48] Sáez J.C., Contreras J.E., Bukauskas F.F., et al. Gap junction hemichannels in astrocytes of the CNS // Acta Physiol Scand. 2003. Vol. 179, N 1. P. 9–22. doi: 10.1046/j.1365-201X.2003.01196.x

[49] Sparey C, Robson SC, Bailey J, Lyall F, et al. The differential expression of myometrial connexin-43, cyclooxygenase-1 and -2, and Gs alpha proteins in the upper and lower segments of the human uterus during pregnancy and labor. J Clin Endocrinol Metab. 1999;84(5):1705–1710. doi: 10.1210/jcem.84.5.5644

[50] Sparey C., Robson S.C., Bailey J., et al. The differential expression of myometrial connexin-43, cyclooxygenase-1 and -2, and Gs alpha proteins in the upper and lower segments of the human uterus during pregnancy and labor // J Clin Endocrinol Metab. 1999. Vol. 84, N 5. P. 1705–1710. doi: 10.1210/jcem.84.5.5644

[51] Mashansky VF. On the possible structural basis of nerveless information transmission in epithelia. Reports of the USSR Academy of Sciences. 1977;235(6):1453–1458. (In Russ.)

[52] Машанский В.Ф. О возможных структурных основах безнервной передачи информации в эпителиях // Доклады АН СССР. 1977. Т. 235, № 6. С. 1453–1458.

[53] Mashansky VF, Markov YuV, Shpunt VKh, et al. Topography of gap junctions in human skin and their possible role in the nerveless transmission of information. Archives of Anatomy, Histology and Embryology. 1983;84(3):53–60. (In Russ.)

[54] Машанский В.Ф., Марков Ю.В., Шпунт В.Х., и др. Топография щелевых контактов кожи человека и их возможная роль в безнервной передаче информации // Архив анатомии, гистологии и эмбриологии. 1983. Т. 84, № 3. С. 53–60.

[55] Arkhipenko VI, Malenkov AG, Gerbilsky LV, et al. Structure and functions of intercellular contacts. Kyiv: Health; 1982. 168 p. (In Russ.)

[56] Архипенко В.И., Маленков А.Г., Гербильский Л.В., и др. Строение и функции межклеточных контактов. Киев: Здоровье, 1982, 168 с.

[57] Kaznacheev VP, Mikhailova LP. Bioinformational function of natural electromagnetic fields. Novosibirsk: Nauka; 1985.182 p. (In Russ.) EDN: RXQADP

[58] Казначеев В.П., Михайлова Л.П. Биоинформационная функция естественных электромагнитных полей. Новосибирск: Наука, 1985. 182 с. EDN: RXQADP

[59] Gurvich AG. Biological field theory. Moscow, Soviet Science; 1944. 155 p. (In Russ.)

[60] Гурвич А.Г. Теория биологического поля. Москва: Советская Наука, 1944. 155 с.

[61] Kanjen D. Bioelectromagnetic fields – a material carrier of biogenetic information. Aura-Z. 1993;(3):42–54. (In Russ.)

[62] Каньджен Д. Биоэлектромагнитные поля — материальный носитель биогенетической информации // Аура-З. 1993. № 3. С. 42–54.

[63] Garyaev PP. Wave genome. Moscow: General Benefit; 1994. 279 p. (In Russ.)

[64] Гаряев П.П. Волновой геном. Москва: Общая Польза, 1994. 279 с.

[65] Alberts B, Bray D, Lewis J, et al. Molecular biology of the cell. 4th ed. New York: Garland Science; 2002.

[66] Alberts B., Bray D., Lewis J., et al. Molecular biology of the cell. 4th ed. New York: Garland Science, 2002.

[67] Bates GW, Edman CD, Porter JC, et.al. Catechol-O-methyl transferase activity in erythrocytes of women taking oral contraceptive steroids. Am J Obstet Gynecol. 1979;133(6):691–698. doi: 10.1016/0002-9378(79)90020-6

[68] Bates G.W., Edman C.D., Porter J.C., et.al. Catechol-O-methyl transferase activity in erythrocytes of women taking oral contraceptive steroids // Am J Obstet Gynecol. 1979. Vol. 133, N 6. P. 691–698. doi: 10.1016/0002-9378(79)90020-6

[69] Casey ML, Hamsell DL, MacDonald PC, et al. NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in human endometrium. Prostaglandins. 1980;19(1):115–128. doi: 10.1016/0090-6980(80)90159-8

[70] Casey M.L., Hamsell D.L., MacDonald P.C., et al. NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity in human endometrium // Prostaglandins. 1980. Vol. 19, N 1. P. 115–128. doi: 10.1016/0090-6980(80)90159-8

[71] Crankshaw DJ, Dyal R. Effects of some naturally occurring prostanoids and some cyclooxygenase inhibitors on the contractility of the human lower uterine segment in vitro. Can J Physiol Pharmacol. 1994;72(8):870–874. doi: 10.1139/y94-123

[72] Crankshaw D.J., Dyal R. Effects of some occurring prostanoids some cyclooxygenase inhibitors on the contractility of the lower uterine segment in vitro // Can J Physiol Pharmacol 1994. Vol. 72, N 8. P. 785–796. doi: 10.1139/y94-123

[73] Germain AM, Smith J, Casey ML, et al. Human fetal membrane contribution to the prevention of parturition: uterotonin degradation. J Clin Endocrinol Metab. 1994;78(2):463–470. doi: 10.1210/jcem.78.2.8106636

[74] Germain A., Smith J., Casey M.L., et al. Human fetal membrane contribution to the prevention of parturition: uterotonin degradation // J Clin Endocrinol Metab. 1994. Vol. 78, N 2. P. 463–468. doi: 10.1210/jcem.78.2.8106636

[75] Petrov-Maslakov MA, Abramchenko VV. Labor pain and pain relief during childbirth. Moscow: Medicine; 1977. 320 p. (In Russ.)

[76] Петров-Маслаков М.А., Абрамченко В.В. Родовая боль и обезболивание родов. Москва: Медицина, 1977. 320 с.

[77] Borovikova NV. Conditions and factors for the productive development of a pregnant woman’s self-concept [dissertation abstract]. Moscow; 1998. 29 p. (In Russ.)

[78] Боровикова Н.В. Условия и факторы продуктивного развития Я-концепции беременной женщины: автореф. дис. … канд. психол. наук. Москва: 1998. 29 c.

[79] Spivak LI, Spivak DL. Changing the state of consciousness: typology, semiotics, psychophysiology. Consciousness and physical reality. 1996;1(4):48–56. (In Russ.) EDN: XASOWR

[80] Спивак Л.И., Спивак Д.Л. Изменение состояния сознания: типология, семиотика, психофизиология // Сознание и физическая реальность. 1996. Т. 1, № 4. С. 48–56. EDN: XASOWR

[81] Spivak LI, Spivak DL, Wistrand K. New psychic phenomena related to normal childbirth. Eur J Psy. 1993;7(4):239–243.

[82] Spivak L.I., Spivak D.L. Wistrand K. New psychic phenomena related to normal childbirth // Eur J Psy. 1993. Vol. 7, N 4. P. 239–243.

[83] Odent M. The caesarean. Free Association Books; 2004. 188 p.

[84] Odent M. The caesarean. Free Association Books, 2004. 188 p.

[85] Hoekzema E., Barba-Müller E., Pozzobon C., et al. Pregnancy leads to long-lasting changes in human brain structure. Nat Neurosci. 2017;20(2):287–296. doi: 10.1038/nn.4458

[86] Hoekzema E., Barba-Müller E., Pozzobon C., et al. Pregnancy leads to long-lasting changes in human brain structure // Nat Neurosci. 2017. Vol. 20, N 2. P. 287–296. doi: 10.1038/nn.4458

[87] Csontos K, Rust M, Hollt V, et.al. Elevated plasma beta-endorphin levels in pregnant women and their neonates. Life Sci. 1979;25(10):835–844. doi: 10.1016/0024-3205(79)90541-1

[88] Csontos K., Rust M., Hollt V., et.al. Elevated plasma beta-endorphin levels in pregnant women and their neonates // Life Sci. 1979. Vol. 25, N 10. P. 835–844. doi: 10.1016/0024-3205(79)90541-1

[89] Lou HC, Tweed WA, Davis JM. Endogenous opioids may protect the perinatal brain hypoxia. Developmental Pharmacology and Therapy. 1989;13(2–4):129–138. doi: 10.1159/000457594

[90] Lou H.C. Endogenous opioids may protect the perinatal brain hypoxia // Developmental Pharmacology and Therapy. 1989. Vol. 13, N 2–4. P. 129–138. doi: 10.1159/000457594

[91] Brekhman GI. The conception of the wave multiple-level interaction between the mother and her unborn child. Int J Prenatal and Perinatal Psychology and Medicine. 2001;13(1/2):83–92.

[92] Brekhman G.I. The conception of the wave multiple-level interaction between the mother and her unborn child // Int J Prenatal and Perinatal Psychology and Medicine. 2001. Vol. 13, N 1/2. P. 83–92.

[93] Perkins AV, Wolfe CD, Eben F, et al. Corticotrophin-releasing hormone-binding protein in human fetal plasma. J Endocrinol. 1995;146(3):395–401. doi: 10.1677/joe.0.1460395

[94] Perkins A.M., et al. Corticotrophin-releasing hormone-binding protein in human fetal plasma // J Endocninol. 1995. Vol. 146, N 3. P. 395–399. doi: 10.1677/joe.0.1460395

[95] Petraglia F, Florio P, Simoncini T, et al. Cord plasma corticotropin-releasing factor-binding protein (CRF-BP) in term and preterm labour. Placenta. 1997;18(2–3):115–119. doi: 10.1016/s0143-4004(97)90082-5

[96] Petraglia F., Florio P., Simoncini T., et al. Cord plasma corticotrophin-releasing factor-binding protein (CRF-BP) in term and preterm labour // Placenta. 1997. Vol. 18, N 2-3. P. 115–121. doi: 10.1016/s0143-4004(97)90082-5

[97] Laatikainen TJ, Räisänen IJ, Salminen KR. Corticotropin-releasing hormone in amniotic fluid during gestation and labor and in relation to fetal lung maturation. Am J Obstet Gynecol. 1988;159(4):891–895. doi: 10.1016/s0002-9378(88)80163-7

[98] Laatikainen T.J., Räisänen I.J., Salminen K.R. Corticotropin-releasing hormone in amniotic fluid during gestation and labor and in relation to fetal lung maturation // Am J Obstet Gynecol. 1988. Vol. 159, N 4. P. 891–895. doi: 10.1016/s0002-9378(88)80163-7

[99] Emanuel RL, Robinson BG, Seely EW, et al. Corticotrophin releasing hormone levels in human plasma and amniotic fluid during gestation. Clin Endocrinol (Oxf). 1994;40(2):257–262. doi: 10.1111/j.1365-2265.1994.tb02477.x

[100] Emanuel R.L., Robinson B.G., Seely E.W., et al. Corticotrophin releasing hormone levels in human plasma and amniotic fluid during gestation // Clin Endocrinol (Oxf). 1994. Vol. 40, N 2. P. 257–262. doi: 10.1111/j.1365-2265.1994.tb02477.x

[101] Aguan K, Carvajal JA, Thompson LP, et al. Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labour. Mol Hum Reprod. 2000;6(12):1141–1145. doi: 10.1093/molehr/6.12.1141

[102] Aguan K., Carvajal J.A., Thompson L.P., et al. Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labor // Mol Hum Reprod. 2000. Vol. 6, N 12. P. 1141–1145. doi: 10.1093/molehr/6.12.1141

[103] Bethin KE, Nagai Y, Sladek R, et al. Microarray analysis of uterine gene expression in mouse and human pregnancy. Mol Endocrinol. 2003;17(8):1454–1469. doi: 10.1210/me.2003-0007

[104] Bethin K.E., Nagai Y., Sladek R., et al. Microarray analysis of uterine gene expression in mouse and human pregnancy // Mol Endocrinol. 2003. Vol. 17, N 8. P. 1454–1469. doi: 10.1210/me.2003-0007

[105] Ledingham MA, Thomson AJ, Jordan F, et al. Cell adhesion molecule expression in the cervix and myometrium during pregnancy and parturition. Obstet Gynecol. 2001;97(2):235–242. doi: 10.1016/s0029-7844(00)01126-1

[106] Ledingham M.A., Thomson A.J., Jordan F., et al. Cell adhesion molecule expression in the cervix and myometrium during pregnancy and parturition // Obstet Gynecol. 2001. Vol. 97, N 2. P. 235–242. doi: 10.1016/s0029-7844(00)01126-1

[107] Osmers RG, Bläser J, Kuhn W, et al. Interleukin-8 synthesis and the onset of labor. Obstet Gynecol. 1995;86(2):223–229. doi: 10.1016/0029-7844(95)93704-4

[108] Osmers R.G., Blaser J., Kuhn W., et al. Interleukin-8 synthesis and the onset of labor // Obstet Gynecol. 1995. Vol. 86, N 2. P. 223–229. doi: 10.1016/0029-7844(95)93704-4

[109] Giannoulias D, Patel FA, Holloway AC, et al. Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium. J Clin Endocrinol Metab. 2002;87(3):1345–1352. doi: 10.1210/jcem.87.3.8317

[110] Giannopulias D., Patel F.A., Holloway A.C., et al. Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium // J Clin Endocrinol Metab. 2002. Vol. 87, N 3. P. 1345–1352. doi: 10.1210/jcem.87.3.8317

[111] Havelock JC, Keller P, Muleba N, et al. Human myometrial gene expression before and during parturition. Biol Reprod. 2005;72(3):707–719. doi: 10.1095/biolreprod.104.032979

[112] Havelock J.C., Patrick K., Muleba N., et al. Human myometrial gene expression before and during parturition // Biology Reprod. 2005. Vol. 72, N 3. P. 707–719. doi: 10.1095/biolreprod.104.032979

[113] Liu X, Helenius D, Skotte L, et al. Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Nat Commun. 2019;10(1):3927. doi: 10.1038/s41467-019-11881-8

[114] Liu X., Helenius D., Skotte L., et al. Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration // Nat Commun. 2019. Vol. 10, N 1. P. 3927. doi: 10.1038/s41467-019-11881-8

[115] Brekhman GI. Breech presentation as a genetic-psychological phenomenon. Journal of Obstetrics and Women’s Diseases. 2015;64(4):26–31.

[116] Брехман Г.И. Тазовое предлежание плода как генетико-психологический феномен // Журнал акушерства и женских болезней. 2015. Т. 64, № 4. С. 26–31.

[117] Dispenza J. Envolve your brain: the science of changing your mind. Health Communications Inc., 2007.

[118] Dispenza J. Envolve your brain: the science of changing your mind. Health Communications Inc., 2007. 528 p.

[119] Dick-Read G. Childbirth without fear. Saint Petersburg: Peter; 1996. 372 p. (In Russ.)

[120] Дик-Рид Г. Роды без страха. Санкт-Петербург: Питер, 1996. 372 с.

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