Immunocytochemistry in diagnostics of endometrial precancer
Tatyana Ivanovna Dzyubiy , Anna Eduardovna Protasova , Grigoriy Aleksandrovich Raskin , Anna Alekseyevna Tsypurdeyeva , Natalya Igorevna Tapilskaya
Journal of obstetrics and women's diseases ›› 2013, Vol. 62 ›› Issue (5) : 35 -40.
Immunocytochemistry in diagnostics of endometrial precancer
Use of the method liquid-based cytology with next immunocytochemical study of endometrium is expedient for the differential diagnosis of endometrial pathology processes. The level of the gene PTEN and steroid receptors expression is higher in cases of simple hyperplasia and hyperplasia without atypia. Increase of the markers p53 and Ki67 expression was found only by atypical endometrial hyperplasia. Positive reaction on CD138 determines the inflammatory process.
endometrial hyperplasia / liquid-based cytology / immunocytochemical study of endometrium
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Dzyubiy T.I., Protasova A.E., Raskin G.A., Tsypurdeyeva A.A., Tapilskaya N.I.
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