Doppler indices of uterine vessels in assessing the ability of endometrial implantation during in vitro fertilization (IVF) cycles

Abstract

Embryo implantation is a multifactorial process. IVF success depends on the quality of the embryo and the receptivity of the endometrium. Ultrasound is non-invasive method to assess the answer of the ovaries and the endometrium in IVF cycles. Color Doppler mapping of the uterine vessels provides information about the degree of vascularization of the uterus and endometrium and ready for implantation. In this article are represented characters uterine blood vessels of 28 infertile women undergoing IVF embryo transfer, followed by 2–3 days of the menstrual cycle, on the day of the trigger and the day of embryo transfer. The comparison of hemodynamic parameters (systolic-diastolic ratio S/D, index of resistance IR, pulsation index PI) of uterine vessels (uterine, arcuate, radial, basal and spiral arteries) was made in 15 pregnant and 13 non-pregnant women after IVF treatment. It was found, that the hemodynamic parameter of uterine vessels on 2–3 days of menstrual cycle does not reflect the ability of endometrium to implantation in IVF cycles. The most effective in the forecast of pregnancy was to determine the mentioned hemodynamic parameters in the basal, spiral arteries of the uterus on the day of the trigger and basal IR and spiral PI arteries on the day of embryo transfer.

Keywords

in vitro fertilization (IVF) / implantation / receptivity / uterine vessels / Doppler / hemodynamic parameters

RIGHTS & PERMISSIONS

Gzgzyan A.M., Niauri D.A., Kogan I.Y., Dzhemlikhanova L.K., Krikheli I.O., Fedorova I.D., Lesik Y.A., Sharfi Y.N., Shilnikova Y.M.