IVF efficiency in different phenotypes of polycystic ovary syndrome

Igor P. Nikolayenkov , Olga E. Kazymova , Dmitry S. Sudakov , Yulia R. Dymarskaya

Journal of obstetrics and women's diseases ›› 2021, Vol. 70 ›› Issue (4) : 81 -90.

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Journal of obstetrics and women's diseases ›› 2021, Vol. 70 ›› Issue (4) : 81 -90. DOI: 10.17816/JOWD61933
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IVF efficiency in different phenotypes of polycystic ovary syndrome

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Abstract

Polycystic ovary syndrome occupies a leading place in the structure of endocrine infertility. This article presents the endocrine and metabolic features of the polycystic ovary syndrome phenotypes, as well as modern concepts of efficiency and complications of the use of assisted reproductive technologies, depending on the specific phenotype. The issues of polycystic ovary syndrome influence on selecting the method of assisted reproductive technologies, as well as possible complications that occur during in vitro fertilization and the features of the pregnancy course remain unresolved. The individualization of the approach seems to be promising when taking into account the differences in the hormonal profile and the features of metabolic disorders in each polycystic ovary syndrome phenotype. That may allow us to take one more step towards improving the effectiveness of in vitro fertilization and reducing the frequency of complications in patients with polycystic ovary syndrome.

Keywords

polycystic ovary syndrome / phenotype / insulin resistance / hyperandrogenemia / obesity / gestational diabetes mellitus / miscarriage / in vitro fertilization / ovarian hyperstimulation syndrome / efficiency

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Igor P. Nikolayenkov, Olga E. Kazymova, Dmitry S. Sudakov, Yulia R. Dymarskaya. IVF efficiency in different phenotypes of polycystic ovary syndrome. Journal of obstetrics and women's diseases, 2021, 70(4): 81-90 DOI:10.17816/JOWD61933

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