Experience of application of fluorescence methods for diagnostics of cervical intraepithelial neoplasias of different degrees
Larisa Anatolyevna Shuliko , Alexandr Vladimirovich Dyachuk , Alexey Nikanorovich Drygin
Journal of obstetrics and women's diseases ›› 2012, Vol. 61 ›› Issue (3) : 47 -52.
Experience of application of fluorescence methods for diagnostics of cervical intraepithelial neoplasias of different degrees
The study includes 132 patients with precancerous cervical disease. Along with a standard practice check-up, all the women have undergone photodynamic diagnostic procedure using photosensitizer Photoditazin. The method allows to increase the visibility of the transformation zone of cervical tissue. The results and advantages of the fluorescent cervicoscopy are compared to the traditional methods, with minimal complications and side effects. Diagnoctic effect of the Photoditazin does not depend on the route of administration
Precancerous cervical disease / photodynamic diagnosis / fluorescent cervicoscopy / fotosensitizer / Photoditazine
| [1] |
Бохман Я. В. Руководство по онкогинекологии. — СПб.: Фолиант, 2002. — 464 с. |
| [2] |
Гилязутдинова З. Ш. Злокачественные новообразования органов репродукции у женщин. — Казань, 2007. — 500 с. |
| [3] |
Денисова Е. Д., Аполихина И. А., Булгакова Н. Н. Флюоресцентная диагностика и фотодинамическая терапия: возможности применения при заболеваниях нижних отделов половых путей // Акушерство и гинекология. — 2010. — № 3. — С. 17–20. |
| [4] |
Заболевания шейки матки: руководство / ред. Ш. Х. Ганцев. — М.: ГЭОТАР-Медиа, 2011. — 160 с. |
| [5] |
Клинические аспекты фотодинамической терапии / А. Ф. Цыб [и др.]. — Калуга, 2009. — 204 с. |
| [6] |
Флуоресцентная диагностика и фотодинамическая терапия фоновых и предраковых заболеваний вульвы с применением 20 % мази «Аласенс» / Е. Г. Новикова [и др.]. // Российский онкологический журнал. — 2009. — № 2. — С. 12–16. |
| [7] |
Huang Z. A. Review of Progress in Clinical Photodynamic Therapy // Technol. Cancer Res. Treat. — 2005. — Vol. 4, № 3. — Р. 283–293. |
| [8] |
Photodynamic diagnosis and therapy in gynecology / P. Soergel [et al.] // J. Environ. Pathol. Toxicol. Oncol. — 2008. — Vol. 27, № 4. — Р. 307–320. |
| [9] |
Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection / D. Zaak [et al.] // J. Urol. — 2001. — Vol.166, № 3. — P. 1665–1669. |
Shuliko L.A., Dyachuk A.V., Drygin A.N.
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