Chromosome 9 inversion infertility treatment. A clinical case

Abstract

This article presents a clinical case of infertility treatment in a woman with chromosome 9 inversion. We herein analyze the clinical significance of this chromosomal rearrangement and the need for genetic counseling at the stage of pregnancy planning. This communication describes a case of successful infertility treatment using assisted reproductive technology and preimplantation genetic testing of aneuploidy.

Keywords

infertility / chromosome 9 inversion / in vitro fertilization / preimplantation genetic testing of aneuploidy / karyotype

References

[1] Mohsen-Pour N, Talebi T, Naderi N, et al. Chromosome 9 inversion: pathogenic or benign? a comprehensive systematic review of all clinical reports. Curr Mol Med. 2022;22(5):385–400. DOI: 10.2174/1566524021666210806161128

[2] Mohsen-Pour N., Talebi T., Naderi N., et al. Chromosome 9 Inversion: pathogenic or benign? A comprehensive systematic review of all clinical reports // Curr. Mol. Med. 2022. Vol. 22. No. 5. P. 385–400. DOI: 10.2174/1566524021666210806161128

[3] Liang S, Yang J, Wu H, et al. Effects of chromosome 9 inversion on IVF/ICSI: a 7-year retrospective cohort study. Mol Genet Genomic Med. 2019;7(9). DOI: 10.1002/mgg3.856

[4] Liang S., Yang J., Wu H., et al. Effects of chromosome 9 inversion on IVF/ICSI: A 7-year retrospective cohort study // Mol. Genet. Genomic. Med. 2019. Vol. 7. No. 9. DOI: 10.1002/mgg3.856

[5] Abdalla EM, El-Kharadly RN. Pericentric inversion of chromosome 9 in a consanguineous couple with molar pregnancies and spontaneous abortions. Lab Med. 2012;43(5):212–216. DOI: 10.1309/LMV84B9GVVYOGZKK

[6] Abdalla E.M., El-Kharadly R.N. Pericentric inversion of chromosome 9 in a consanguineous couple with molar pregnancies and spontaneous abortions // Lab. Med. 2012. Vol. 43. No. 5. P. 212–216. DOI: 10.1309/LMV84B9GVVYOGZKK

[7] Mozdarani H, Meybodi AM, Karimi H. Impact of pericentric inversion of Chromosome 9 [inv (9) (p11q12)] on infertility. Indian J Hum Genet. 2007;13(1):26–29. DOI: 10.4103/0971-6866.32031

[8] Mozdarani H., Meybodi A.M., Karimi H. Impact of pericentric inversion of Chromosome 9 [inv (9) (p11q12)] on infertility // Indian J. Hum. Genet. 2007. Vol. 13. No. 1. P. 26–29. DOI: 10.4103/0971-6866.32031

[9] Merrion K, Maisenbacher M. Pericentric inversion (Inv) 9 variant-reproductive risk factor or benign finding? J Assist Reprod Genet. 2019;36(12):2557–2561. DOI: 10.1007/s10815-019-01601-y

[10] Merrion K., Maisenbacher M. Pericentric inversion (Inv) 9 variant-reproductive risk factor or benign finding? // J. Assist. Reprod. Genet. 2019. Vol. 36. No. 12. P. 2557–2561. DOI: 10.1007/s10815-019-01601-y

[11] Šípek A Jr, Panczak A, Mihalová R, et al. Pericentric inversion of human chromosome 9 epidemiology study in czech males and females. Folia Biol (Praha). 2015;61(4):140–146.

[12] Šípek A. Jr., Panczak A., Mihalová R., et al. Pericentric inversion of human chromosome 9 epidemiology study in czech males and females // Folia Biol (Praha). 2015. Vol. 61. No. 4. P. 140–146.

[13] Kumar M, Thatai A, Chapadgaonkar SS. Homozygosity and heterozygosity of the pericentric inversion of chromosome 9 and its clinical impact. J Clin Diagn Res. 2012;6:816–820.

[14] Kumar M., Thatai A., Chapadgaonkar S.S. Homozygosity and heterozygosity of the pericentric inversion of chromosome 9 and its clinical impact // J. Clin. Diagn. Res. 2012. Vol. 6. P. 816–820.

[15] Muthuvel A, Ravindran M, Chander A, et al. Pericentric inversion of chromosome 9 causing infertility and subsequent successful in vitro fertilization. Niger Med J. 2016;57(2):142–144. DOI: 10.4103/0300-1652.182080

[16] Muthuvel A., Ravindran M., Chander A., et al. Pericentric inversion of chromosome 9 causing infertility and subsequent successful in vitro fertilization // Niger. Med. J. 2016. Vol. 57. No. 2. P. 142–144. DOI: 10.4103/0300-1652.182080

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