Comparative evaluation of the antistress effect of phenazepam, melatonin and their combination

Eduard B. Arushanian; Olga Vladimirovna; Eduard Vladimirovich Beyer

doi:10.17816/RCF191107-110

Reviews on Clinical Pharmacology and Drug Therapy ›› 2021, Vol. 19 ›› Issue (1) :107 -110. DOI: 10.17816/RCF191107-110

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Comparative evaluation of the antistress effect of phenazepam, melatonin and their combination

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Abstract

Phenazepam and melatonin reduce anxiety in stressed rats, and their anxiolytic effect is enhanced in combination. Melatonin also limits stress-induced increases in sympathetic activity and eliminates the dysregulatory effect of phenazepam on the main indicators of heart rate variability.

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phenazepam / melatonin / anti-stress effect

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Eduard B. Arushanian, Olga Vladimirovna, Eduard Vladimirovich Beyer. Comparative evaluation of the antistress effect of phenazepam, melatonin and their combination. Reviews on Clinical Pharmacology and Drug Therapy, 2021, 19(1): 107-110 DOI:10.17816/RCF191107-110

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References

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