The need to create and implement a platform for managing the professioyal reliability of military personnel of the armed forces of the russian federation, based on the principles of personalizet medicine

Abstract

The article analyzes modern federal programs aimed at preserving the health and well-being of the population and creating a comfortable and safe environment for life and work. The article describes the arsenal of strategic directions for assessing the risk of developing diseases, diagnostic approaches and scientific principles that contribute to the successful implementation of evaluation measures. The possibility of clarifying the cardiovascular risk in the study of the role of military-professional factors in the formation of cardiovascular pathology in military personnel of the Armed Forces of the Russian Federation is discussed. The article analyzes the effectiveness of traditional diagnostic methods used by the medical service, as well as ways to improve this efficiency when using molecular genetic studies to search for associations with risk factors for neuropsychic and cardiovascular pathology. The article considers the practical necessity of creating a professional reliability management platform based on the principles of personalized medicine, which contributes to prolonging professional longevity and improving the combat readiness of servicemen of the Armed Forces of the Russian Federation. Such a method of implementing the professional reliability management platform will significantly increase the informativeness of traditional methods of early diagnosis of cardiovascular and neuropsychic pathology.

Keywords

professional reliability / personalized medicine / professional longevity / risk factors for the development of cardiovascular diseases / stress / prevention of non-communicable diseases / high-tech healthcare / molecular genetic studies

References

[1] Talashmanova K. On the problem of understanding the professional reliability of the subject. Human capital. 2020;3(135):239–245. (In Russ.)

[2] Талашманова К.А. К проблеме понимания профессиональной надежности субъекта // Человеческий капитал. 2020. № 3 (135). С. 239–245.

[3] Interstate standard GOST R 27.002-89 Reliability in technology. Basic concepts. Industrial product dependability. General concepts. Terms and definitions. Moscow; 1989. (In Russ.)

[4] Межгосударственный стандарт ГОСТ Р 27.002-89 Надежность в технике. Основные понятия. Industrial product dependability. General concepts. Terms and definitions. М.: Издательство стандартов, 1989.

[5] Karpovich OG. The practice of the US conducting information warfare operations in the field of foreign policy. National security. Nota bene. 2017;1:112–126. doi: 10.7256/2454-0668.2017.1.20026. (In Russ.)

[6] Карпович О.Г. Практика проведения США операций информационной войны в сфере внешней политики. Национальная безопасность // Nota bene. 2017. № 1. С. 112–126.

[7] Trishkin D, Fisun A, Makiev R, et al. The current state and prospects for the development of personalized medicine, high-tech healthcare and health-preserving technologies in the medical service of the Armed Forces of the Russian Federation. Bulletin of the Russian Military Medical Academy. 2019;3(67):145–150. (In Russ.)

[8] Тришкин Д.В., Фисун А.Я., Макиев Р., и др. Современное состояние и перспективы развития персонализированной медицины, высокотехнологичного здравоохранения и технологий здоровьесбережения в медицинской службе Вооруженных сил Российской Федерации // Вестник Российской военно-медицинской академии. 2019. № 3 (67). С. 145–150.

[9] Fiatal S, Adany R. Application of single-nucleotide polymorphism-related risk estimates in identification of increased genetic susceptibility to cardiovascular diseases: a literature review. Frontiers in public health. 2018;5:358. doi: https://doi.org/10.3389/fpubh.2017.00358

[10] Fiatal S., Adany R. Application of single-nucleotide polymorphism-related risk estimates in identification of increased genetic susceptibility to cardiovascular diseases: a literature review // Frontiers in public health. 2018. Vol. 5. P. 358. doi: https://doi.org/10.3389/fpubh.2017.00358

[11] Miao L, Yin R, Yang S, et al. Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke. Lipids in health and disease. 2017 Oct 5;16(1):1–9. doi: https://doi.org/10.1186/s12944-017-0584-5

[12] Miao L., Yin R., Yang S., et al. Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke // Lipids in health and disease. 2017. Vol. 16, No. 1. P. 1–9. doi: https://doi.org/10.1186/s12944-017-0584-5

[13] Yang J. Of markets and rights: Discourse in the 2008 and 2013 Global Action Plan for the Prevention and Control of Noncommunicable Diseases. Annals of Global Health. 2016; 82(3):472. doi: http://doi.org/10.1016/j.aogh.2016.04.293

[14] Yang J. Of markets and rights: Discourse in the 2008 and 2013 Global Action Plan for the Prevention and Control of Noncommunicable Diseases // Annals of Global Health. 2016. Vol. 82, No. 3. P. 472. doi: http://doi.org/10.1016/j.aogh.2016.04.293

[15] Makiev G, Hestanova S, Kertanov R et al. CRISPR-CAS9 genome editing system as a research tool and method for gene therapy for Fabry disease. Colloquium-journal. 2020;3(55):56–58. (In Russ.)

[16] Макиев Г.Г., Гестанова С., Кертанов Р., и др. Система редактирования генома CRISPR-CAS9 как средство изучения и способ генной терапии болезни Фабри // Colloquium-journal. 2020. № 3 (55). С. 56–58.

[17] Stepanov T, Innovative CRISPR / CAS9 method — as a potential treatment for human diseases. 2019:122–125. (In Russ.)

[18] Степанов Т.В. Инновационный метод CRISPR/CAS9 как потенциальное средство лечения заболеваний человека // Наука, технология, техника: перспективные исследования и разработки. 2019. С. 122–125.

[19] Prutkoj A, Konstantinova T, Nikitina A. On the advantages, disadvantages and achievements of CRISPR-CAS9. Problems and Prospects for the Development of Russia: Youth Look into the Future. 2020;3:124–126. (In Russ.)

[20] Пруткой А.С., Константинова Т.В., Никитина А.Л. О преимуществах, недостатках и достижениях CRISPR-CAS9 // Проблемы и перспективы развития России: молодежный взгляд в будущее. 2020. С. 124–126.

[21] Cherkashin D, Makiev R, Kirichenko Ju. New strategy to improve the effectiveness of prevention of cardiovascular diseases in the Armed Forces of the Russian Federation. Bulletin of the Russian Military Medical Academy. 2017;36(3):34–39. (In Russ.)

[22] Черкашин Д.В., Макиев Р., Кириченко Ю. Новая стратегия повышения эффективности профилактики сердечно-сосудистых заболеваний в Вооруженных силах Российской Федерации // Известия Российской Военно-медицинской академии. 2017. Т. 36, № 3. С. 34–39.

[23] Kryukov E. Change in nonspecific protection and immunity in military personnel in the process of adaptation to military service. Military Medical Journal. 2003;12:60. (In Russ.)

[24] Крюков Е.В. Изменение неспецифической защиты и иммунитета у военнослужащих в процессе адаптации к военной службе // Военно-медицинский журнал 2003. №. 12. С. 60.

RIGHTS & PERMISSIONS

Kutelev G.G., Cherkashin D.V., Trishkin T.V., Kryukov E.V., Fisun A.Y., Marchenko M.A., Shulenin K.S., Krivoruchko A.B., Sobolev A.D.