Сhronic gastritis: impaired motor-evacuation function of the stomach
I. M. Pavlovich , G. A. Al’per , A. V. Gordienko , D. I. Proskunov , V. V. Yakovlev
Bulletin of the Russian Military Medical Academy ›› 2020, Vol. 22 ›› Issue (4) : 37 -42.
Сhronic gastritis: impaired motor-evacuation function of the stomach
The effect of morphological changes in the gastric mucosa on the motor-evacuation function of the stomach was evaluated in 90 patients with chronic atrophic gastritis and 93 patients with chronic non-atrophic gastritis aged 18 to 82 years. Motor function disturbances were discovered of 90% of patients with chronic atrophic gastritis and 80,6% – with chronic non-atrophic gastritis. It was established that the pyloric insufficiency compared with its spasm was significantly more (p<0,01) often in chronic atrophic gastritis. Insufficiency of the lower esophageal sphincter in patients with atrophic gastritis was significantly (p<0,01). Insufficiency of the lower esophageal sphincter in combination with duodenogastric reflux in patients with chronic atrophic gastritis was significantly more (p<0,01) often observed during diffuse atrophy, i. e. when mucous membrane of stomach corpus and antrum is involved in the process. With the localization of atrophy in the antrum alone, pyloric insufficiency was observed significantly more (p <0,01) often than spasm. Thus, an interrelation between the insufficiency of the lower esophageal and pyloric sphincters with the diffuse atrophic process has been established. There are no significant differences of disorders of gastric motor function in patients with different types of chronic gastritis. Accelerated evacuation from the stomach with localization of atrophy in the mucous membrane of the stomach corpus is more (p <0,01) often observed in patients with chronic atrophic gastritis.
chronic gastritis / atrophy of the gastric mucosa / motor disorders of the stomach / pyloric insufficiency/spasm / duodenogastric reflux / food evacuation / chronic non- atrophic gastritis / the body of stomach / antral part of the stomach
| [1] |
Аруин, Л.И. Хронический гастрит / Л.И. Аруин [и др.]. – Амстердам, 1993. – 362 с. |
| [2] |
Аруин, Л.И. Морфологическая диагностика болезней желудка и кишечника / Л.И. Аруин, Л.Л. Капуллер, В.А. Исаков. – М.: Триада-Х, 1998. – 484 с. |
| [3] |
Каприн, А.Д. Злокачественные новообразования в России в 2018 году (заболеваемость и смертность) / А.Д. Каприн, В.В. Старинский, Г.В. Петрова. – М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России, 2019. – 250 с. |
| [4] |
Минушкин, О.Н. Хронический гастрит / О.Н. Минушкин, И.В. Зверков // Лечащий врач. – 2003. – № 3. – С. 24-31. |
| [5] |
Павлович, И.М. Особенности морфологической структуры и моторно-эвакуаторной дисфункции желудка при различных типах хронического гастрита / И.М. Павлович, В.Ю. Голофеевский // Вестн. Санкт-Петербургской гос. мед. акад. им. И.И. Мечникова. – 2005. – № 4 (6). – С. 131–134. |
| [6] |
Рысс, Е.С. Современные представления о хроническом гастрите (определение, механизмы развития, классификация, клиническая картина) // Тер. архив. – 1999. – № 2. – С. 7–13. |
| [7] |
Самигуллин, М.Ф. Эндоскопическая диагностика моторных нарушений верхних отделов желудочно-кишечного тракта / М.Ф. Самигуллин, В.Ю. Муравьев, А.И. Иванов // Мед. альманах. – 2008. – № 2. – С. 33–34. |
| [8] |
Ткаченко, Е.И. Гастроэнтерология: руководство для врачей / Е.И. Ткаченко. – СПб.: СпецЛит, 2013. – 637 с. |
| [9] |
Хомяков, В.М. Современные представления о факторах риска развития рака желудка / В.М. Хомяков [и др.] // Росс. журн. гастроэнтерологии, гепатологии, колопроктологии. – 2017. – № 27 (6). – С. 78–86. |
| [10] |
Щербо А.П. Заболеваемость взрослого населения Российской Федерации гастритами и язвенной болезнью: тенденции последних двадцати лет / А.П. Щербо, Н.В. Ширинская // Проф. и клин. мед. – 2016. – № 2 (59). – С. 21–25. |
| [11] |
Anderson, W.F. Age-specific trends in incidence of noncardia gastric cancer in US adults / W.F. Anderson [et al.] // JAMA. – 2010. – Vol. 303 (17). – 1723–1728. |
| [12] |
Correa, P. A model for gastric cancer epidemiology / P. Correa [et al.] // Lancet. – 1975. – № 2 (7924). – Р. 58–60. |
| [13] |
Dinis-Ribeiro, M. European Society of Gastro- intestinal Endoscopy; European Helicobacter Study Group; European Society of Pathology; Sociedade Portuguesa de Endoscopia Digestiva. Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED) / M. Dinis-Ribeiro [et al.] // Endoscopy. – 2012. – № 44 (1). – Р. 74–94. |
| [14] |
Dixon, M.F. Classification and grading of gastritis / M.F. Dixon [et al.] // Am. J. Surg. Pathol. – 1996. – № 20 (10). – Р. 1161–1181. |
| [15] |
El-Zimaity, H.M. Patterns of gastric atrophy in intestinal type gastric carcinoma / H.M. El-Zimaity [et al.] // Cancer. – 2002. – № 94 (5). – Р. 1428–1436. |
| [16] |
Jencks, D.S. Overview of Current Concepts in Gastric Intestinal Metaplasia and Gastric Cancer / D.S. Jencks [et al.] // Gastroenterology & hepatology. – 2018. – № 14 (2). – Р. 92–-101. |
| [17] |
Kapadia, C.R. Gastric atrophy, metaplasia and dysplasia. A clinical perspective / C.R. Kapadia // J. Clin. Gastroenterol. – 2003. – № 36. – Р. 29–36. |
| [18] |
Munkholm, P. Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease / P. Munkholm // Aliment Pharmacol. Ther. – 2003. – № 18 (s2). – Р. 15–21. |
| [19] |
Park, Y.H. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer / Y.H. Park, N. Kim // Cancer. Prev. –2015. – № 20 (1). – Р. 25–40. |
| [20] |
Schlansky, B. Epidemiology of noncardia gastric adenocarcinoma in the United States / B. Schlansky, A. Sonnenberg // Am. J. Gastroenterol. – 2011. – № 106. – Р. 1978–1985. |
| [21] |
Song, H. Incidence of gastric cancer among patients with gastric precancerous lesions: observational cohort study in a low risk Western population / H. Song [et al.] // BMJ. – 2015. – № 351. – Р. 386. |
| [22] |
Song, H. Increase in the Prevalence of Atrophic Gastritis Among Adults Age 35 to 44 Years Old in Northern Sweden Between 1990 and 2009 / H. Song [et al.] // Clin. Gastroenterol. Hepatol. – 2015. – № 13 (9). – Р. 1592–1600. |
| [23] |
Song, J.H. Risk Factors for Gastric Tumorigenesis in Underlying Gastric Mucosal Atrophy / J.H. Song [et al.] // Gut Liver. – 2017. – № 11 (5). – Р. 612–619. |
| [24] |
Spence, A.D. Adenocarcinoma risk in gastric atrophy and intestinal metaplasia: a systematic review / A.D. Spence [et al.] // BMC Gastroenterol. – 2017. – № 17 (1). – Р. 157. |
| [25] |
Zullo, A. Follow-up of intestinal metaplasia in the stomach: When, how and why / A. Zullo [et al.] // World J. Gastrointest. Oncol. – 2012. – № 4 (3). – Р. 30–36. |
Pavlovich I.M., Al’per G.A., Gordienko A.V., Proskunov D.I., Yakovlev V.V.
/
| 〈 |
|
〉 |