Characteristics of discolorites, state of enamel and care-resistance factors in patients with atopic dermatitis

Abstract

Features of the state of tooth enamel, factors of caries resistance in atopic dermatitis in adults are considered. The following methods were used: assessment of degree of teeth darkening; assessment of gingival condition using a chromatic indicator (alphabetic and digital); determination of mineralization of enamel and oral fluid by calcium and phosphorus ions with calculation of remineralization index; test for enamel resistance. As a result, a conclusion was drawn about the type of solubility and mineralization of enamel. Caries resistance of enamel and dentine was also assessed; determined the degree of dissemination of cariogenic and resident bacterial species by bacteriological examination of plaque; concentration of the antimicrobial peptide catelicidin LL-37 in the oral and gingival fluid was measured. To assess the severity and prevalence of atopic dermatitis, the Scoring Atopic Dermatitis index was calculated. It was found that in patients with atopic dermatitis, pronounced discoloritis of hard tooth tissues was observed, which was accompanied, mainly, by high and medium degree of acid resistance of enamel, by normal content of calcium and phosphorus in oral fluid and in acid bioptate of enamel. In comparison with patients who had discolored teeth without any allergic pathology, despite the absence of color differences, mineral metabolism and enamel solubility, the structure of types of solubility and mineralization of enamel was disrupted in patients suffering from atopic dermatitis. In addition, in these patients, increased colonization of acid-producing cariespathogenic streptococcal microflora was detected, with a decrease in the activity of congenital antimicrobial immune response. These features should be taken into account during the whitening procedures, as they may affect their effectiveness.

Keywords

atopic dermatitis / discolorations of teeth / antimicrobial peptides / mouth fluid / oral microbiota / caries resistance / mineral exchange of tooth enamel / solubility of tooth enamel

References

[1] Коростовцев, Д.С. Индекс SCORAD - объективный и стандартизированный метод оценки поражения кожи при атопическом дерматите / Д.С. Коростовцев, И.В. Макарова, В.А. Ревякина // Аллергология. - 2000. - № 3. - С. 39-43.

[2] Кулакова, Е.В. Роль эндогенных антимикробных пептидов (кателицидин LL-37) в развитии кариеса у детей с атопическим дерматитом / Е.В. Кулакова [и др.] // Лечение и профилактика. - 2013. - № 1 (5). - С. 73-76.

[3] Торопова, Н.П. Атопический дерматит детей и подростков - эволюция взглядов на патогенез и подходы к терапии / Н.П. Торопова, К.Н. Сорокина, Т.С. Лепешкова // Росс. журн. кожных и венерических болезней. - 2014. - № 6. - С. 50-59.

[4] Феденко, Е.С. Патогенетическое обоснование интегрального подхода к наружной терапии атопического дерматита / Е.С. Феденко [и др.] // Росс. аллергологический журн. - 2012. - № 4. - С. 50-55.

[5] Хаитов, Р.М. Атопический дерматит: рекомендации для практических врачей. Российский национальный согласительный документ по атопическому дерматиту / Р.М. Хаитов, А.А. Кубанова.- М.: Фармарус-Принт. - 2002. - 192 с.

[6] Чикин, В.В. Федеральные клинические рекомендации по ведению больных атопическим дерматитом / В.В. Чикин [и др.]. - М.: Росс. общество дерматовенерологов и косметологов. - 2013. - 40 с.