Doctor of medicine – the histologist Vera Mikhaylovna Danchakova (to the 140 anniversary since birth)

Abstract

In may 2018 there will be 150 years from the date of foundation of the department of histology with a course of embryology of S.M. Kirov Military Medical Academy. Some unknown facts about the doctor of medicine – the histologist Vera Mikhaylovna Danchakova are submitted. She was a student of professor A.A. Maximov, and one of the first women who defended the dissertation on histology in Imperial Military Medical Academy in 1907. V.M. Danchakova firmly stood on positions of supporters of the unitary theory of blood formation. Short work in the A.A. Maximov’s histologic laboratory predetermined the sphere of her scientific interests for many years. In many-sided creativity of V.M. Danchakova several directions of her scientific research are traced – there are: an origin of blood cells, the doctrine about a stem cell and its differentiation potentialities; a research of tumoral growth, the role of immune system in carcinogenesis and tissue transplantation. The considerable period of life V.M. Danchakova worked abroad. Her works of tissue cultivation in vivo on a horio-allantois of a chicken embryo are of high priority. In 1916 her article “Origin of the blood cell. Development of the hematopoietic organs and regeneration of the blood cell from the standpoint of the monophyletic school” was published, in this article she was the first who suggests a possibility of transformation of a stem cell in a patholologically changed cell. Under the leadership of V.M. Danchakova in laboratory of an experimental morphogenesis of a research institute named after K.A. Timiryazeva (Moscow) the issues of an origin of gametes and regularity of individual development of an organism were studied. V.M. Danchakova is the author of the original technique of a research of influence of sex hormones on a male differentiation that is reflected in several of her monographs.

Keywords

Vera Mikhaylovna Danchakova / Military Medical Academy / A. A. Maximov / unitary theory of a hemopoiesis / stem cell / tissue cultivation / laboratory of an experimental morphogenesis of a research institute of name K.A. Timiryazeva / the Rockefeller institute for medical research / anatomical laboratory of Columbia University / gametes / embryogenesis

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