About oncological safety of cell-assisted lipotransfer application in the reconstructive surgery of mammary gland

Abstract

Despite the obvious improvement in the examination and treatment results in patients with malignant tumors, the problems of providing medical care to this contingent of patients are still preserved. Until now, surgeries (radical mastectomy, lumpectomy) remain the main method of breast cancer treatment. Such operations, as a rule, lead to mammary glands deformities and life quality worsening of these patients. Currently, reconstructive surgery is an integral stage of the psychological rehabilitation of women after breast cancer surgical treatment. The data of researchers, who have experience in mammary glands deformities correction after surgical treatment of breast cancer, was specifically studied. In the article the information about intercellular interaction, which occurs when adipose derived stem cells are implanted into the area of malignant tumor surgical removal, was analyzed. Possible options of autologous adipose tissue (containing stem cells) transplantation application in cases of correction of breast deformities after cancer removal are discussed. Based on the results of practice of breast surgery specialists, authors concluded, that autologous adipose tissue (containing stem cells) transplantation in cases of correction of breast deformities after the surgical treatment of malignant tumors is nowadays possible by indications. Based on the information presented in publications of scientists from different countries, promising areas of research have been defined for studying the aspects of oncological safety of transplantation of autologous fat tissue (containing stem cells) for correction of breast deformities after malignant tumor removal.

Keywords

regenerative medicine / plastic surgery / breast cancer / mesenchymal stem cells / adipose tissue / oncological safety / malignant tumors

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