Prevention of hemorrhagic complications during hybrid interference in the sleepy and coronary arteries under conditions of hypo-agregation and hypocaagulation

Anton N. Kazantsev , Konstantin P. Chernykh , Goderzi Sh. Baghdavadze

Bulletin of the Russian Military Medical Academy ›› 2021, Vol. 23 ›› Issue (2) : 67 -74.

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Bulletin of the Russian Military Medical Academy ›› 2021, Vol. 23 ›› Issue (2) : 67 -74. DOI: 10.17816/brmma26306
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Prevention of hemorrhagic complications during hybrid interference in the sleepy and coronary arteries under conditions of hypo-agregation and hypocaagulation

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Abstract

Hemorrhagic complications in patients after hybrid interventions including percutaneous coronary intervention and carotid endarterectomy are analyzed. Demonstrate a new method of hemostasis and wound drainage after carotid endarterectomy. It was found that at the preoperative stage, the coagulogram parameters were within the normal range, but the aggregatogram showed hypoagregation for two of the four inducers in all 84 operated patients. After the completion of the second stage of revascularization, the absolute partial thrombosed time in all patients was five to six times higher than normal in the coagulogram parameters. According to the aggregatogram, there was a total hypo-aggregation. All acute hematomas after carotid endarterectomy requiring revision were formed in patients with the traditional method of hemostasis and wound drainage after carotid endarterectomy (p = 0.038), which was associated with more frequent damage to the cranial nerves (p = 0.0002). Thus, the combined endpoint, including the indicator of cranial nerve damage + acute hematoma in patients with the traditional method of hemostasis and wound drainage after carotid endarterectomy, significantly exceeded it in patients who used a new tactic (local hemostatics with minimal electrocoagulation and installation of two drains in the paravasal and clitoral space) (p < 0.0001). There were no cases of wound complications in the area of carotid endarterectomy. Thus, the new technique of hemostasis and wound drainage after carotid endarterectomy against the background of hypocoagulation and hypoagregation has shown its effectiveness and preventive role in the prevention of hemorrhagic complications, damage to the cranial nerves.

Keywords

carotid endarterectomy / percutaneous coronary intervention / acute hematoma / revision / hemorrhagic complications / neuropathy / ischemic stroke / drainage of the postoperative wound / cerebral atherosclerosis / coagulation

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Anton N. Kazantsev, Konstantin P. Chernykh, Goderzi Sh. Baghdavadze. Prevention of hemorrhagic complications during hybrid interference in the sleepy and coronary arteries under conditions of hypo-agregation and hypocaagulation. Bulletin of the Russian Military Medical Academy, 2021, 23(2): 67-74 DOI:10.17816/brmma26306

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References

[1]

Mousa A, Broce M. Carotid endarterectomy before and after CREST. J Endovasc Ther. 2016;23(3):536–537. DOI: 10.1177/1526602816640817

[2]

Mousa A., Broce M. Carotid endarterectomy before and after CREST // J. Endovasc. Ther. 2016. Vol. 23. No. 3. P. 536–537. DOI: 10.1177/1526602816640817

[3]

Hopkins LN, Roubin GS, Chakhtoura EY, et al. The carotid revascularization endarterectomy versus stenting trial: credentialing of interventionalists and final results of lead-in phase. J Stroke Cerebrovasc Dis. 2010;19(2):153–162. DOI: 10.1016/j.jstrokecerebrovasdis.2010.01.001

[4]

Hopkins L.N., Roubin G.S, Chakhtoura E.Y., et al. The carotid revascularization endarterectomy versus stenting trial: credentialing of interventionalists and final results of lead-in phase // J. Stroke Cerebrovasc. Dis. 2010. Vol. 19. No. 2. P. 153–162. DOI: 10.1016/j.jstrokecerebrovasdis.2010.01.001

[5]

Barbarash LS, Tarasov RS, Kazantsev AN, et al. Factors of poor prognosis of various surgical strategies for the treatment of patients with combined lesions of the coronary and brachycephalic arteries in the long-term postoperative period. Cardiology and Cardiovascular Surgery. 2017;10(2):22–39. (In Russ.). DOI: 10.17116/kardio201710222-39

[6]

Барбараш Л.С., Тарасов Р.С., Казанцев А.Н., и др. Факторы неблагоприятного прогноза различных хирургических стратегий лечения пациентов с сочетанным поражением коронарных и брахицефальных артерий в отдаленном послеоперационном периоде // Кардиология и сердечно-сосудистая хирургия. 2017. Т. 10, № 2. С. 22–39. DOI: 10.17116/kardio201710222-39

[7]

Kazantsev AN. Personalized choice of the optimal strategy for surgical treatment of patients with combined lesions of the coronary bed and brachiocephalic arterie. Siberian Medical Journal (Tomsk). 2017;32(1):14–23. (In Russ.).

[8]

Казанцев А.Н. Персонифицированный выбор оптимальной стратегии хирургического лечения пациентов с сочетанным поражением коронарного русла и брахиоцефальных артерий // Сибирский медицинский журнал (г. Томск). 2017. Т. 32, № 1. С. 14–23.

[9]

National guidelines for the management of patients with diseases of the brachiocephalic arteries. Angiology and vascular surgery. 2013;19(2):4–68. (In Russ.).

[10]

Национальные рекомендации по ведению пациентов с заболеваниями брахиоцефальных артерий // Ангиология и сосудистая хирургия. 2013. Т. 19, № 2. С. 4–68.

[11]

Aboyans V, Ricco JB, Bartelink MEL, et al. ESC Scientific Document Group. 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS). Eur Heart J. 2018;39(9):763–816. DOI: 10.1093/eurheartj/ehx095

[12]

Aboyans V., Ricco J.B., Bartelink M.E.L., et al. ESC Scientific Document Group. 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS) // Eur. Heart J. 2018. Vol. 39. No. 9. P. 763–816. DOI: 10.1093/eurheartj/ehx095

[13]

Vinogradov RA, Matusevich VV. Results of the use of glomus-sparing carotid endarterectomy. Medical Bulletin of the North Caucasus. 2017;12(4):467–468. (In Russ.). DOI: 10.14300/mnnc.2017.12130

[14]

Виноградов Р.А., Матусевич В.В. Результаты применения гломуссохраняющих каротидных эндартерэктомий // Медицинский вестник Северного Кавказа. 2017. Т. 12. № 4. С. 467–468. DOI: 10.14300/mnnc.2017.12130

[15]

Pokrovsky AV. "Classical" carotid endarterectomy. Angiology and vascular surgery. 2001;1:101–104. (In Russ.).

[16]

Покровский А.В. «Классическая» каротидная эндартерэктомия // Ангиология и сосудистая хирургия. 2001. № 1. С. 101–104.

[17]

Kazantsev AN, Tarasov RS, Burkov NN, et al. Carotid endarterectomy: three-year follow-up results in a single-center register. Angiology and Vascular Surgery. 2018;24(3):101–108. (In Russ.).

[18]

Казанцев А.Н., Тарасов Р.С., Бурков Н.Н., и др. Каротидная эндартерэктомия: трехлетние результаты наблюдения в рамках одноцентрового регистра // Ангиология и сосудистая хирургия. 2018. Т. 24, № 3. С. 101–108.

[19]

Kazantsev AN, Tarasov RS, Burkov NN, et al. Hospital results of percutaneous coronary intervention and carotid endarterectomy in hybrid and staged modes. Angiology and Vascular Surgery. 2019;25(1):101–107. (In Russ.). DOI: 10.33529/angio2019114

[20]

Казанцев А.Н., Тарасов Р.С., Бурков Н.Н., и др. Госпитальные результаты чрескожного коронарного вмешательства и каротидной эндартерэктомии в гибридном и поэтапном режимах // Ангиология и сосудистая хирургия. 2019. Т. 25, № 1. С. 101–107. DOI: 10.33529/angio2019114

[21]

Kazantsev AN, Chernykh KP, Lider RYu, et al. Comparative results of classical and eversional carotid endarterectomy. Cardiology and cardiovascular surgery. 2020;13(6):550–555. (In Russ.). DOI: 10.17116/kardio202013061550

[22]

Казанцев А.Н., Черных К.П., Лидер Р.Ю., и др. Сравнительные результаты классической и эверсионной каротидной эндартерэктомии // Кардиология и сердечно-сосудистая хирургия. 2020. Т. 13, № 6. С. 550–555. DOI: 10.17116/kardio202013061550

[23]

Vinogradov RA, Pykhteev VS, Lashevich KA. Long-term results of open surgical and endovascular treatment of stenosis of the internal carotid arteries. Angiology and Vascular Surgery. 2017;23(4):164–170. (In Russ.).

[24]

Виноградов Р.А., Пыхтеев В.С., Лашевич К.А. Отдаленные результаты открытого хирургического и эндоваскулярного лечения стенозов внутренних сонных артерий // Ангиология и сосудистая хирургия. 2017. Т. 23, № 4. С. 164–170.

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