Early markers of pulmonary hypertension in young and middle-aged men after myocardial infarction

Abstract

The article presents the results of the study, which included 454 men aged 18 to 60 years with a verified diagnosis of myocardial infarction, who were treated in hospitals of St. Petersburg from 2000 to 2015. Patients were divided into two groups according to the presence or absence of pulmonary hypertension, detected by echocardiography at the end of the third week of the disease. The main risk factors of cardiovascular diseases affecting the development of pulmonary hypertension in the subacute period of myocardial infarction – alcohol abuse and the presence of occupational hazards. The risk of pulmonary hypertension in the subacute period of myocardial infarction is significantly increased in patients with a history of coronary heart disease for more than five years, suffering from hypertension for more than seven years and chronic heart failure for more than a year, as well as in patients with obesity for more than 10 years. The development of repeated, recurrent and recurrent myocardial infarction increases the risk of pulmonary hypertension Patients with a mixed version of the clinical course of myocardial infarction, as well as with the results of the evaluation of the prognostic scale for assessing the risk of death in acute coronary syndrome more than 129 points and the Norris index more than 9.2 points have a higher risk of developing pulmonary hypertension in the subacute period of myocardial infarction. Increased levels of sodium, cholesterol, and calcium in the first hours of myocardial infarction, potassium, chlorine and creatinine levels at the end of the third week of the disease increase the risk of pulmonary hypertension in the subacute period of myocardial infarction. The most significant predictors of pulmonary hypertension in the subacute period of myocardial infarction were signs of left ventricular systolic dysfunction and dilation of the left heart.

Keywords

pulmonary hypertension / myocardial infarction / early markers / young and middle age / systolic dysfunction / echocardiography / risk factors / subacute period / electrolytes

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RIGHTS & PERMISSIONS

Kudinova A.N., Gordienko A.V., Sotnikov A.V., Nosovich D.V., Epifanov S.Yu.