Current trends in the treatment of hypertrophic scars

Abstract

BACKGROUND: The therapeutic arsenal for the treatment of hypertrophic scars and keloids has expanded significantly in recent years. Traditional methods of treatment, such as intraocular injection of corticosteroids, pressure therapy and cryotherapy, are increasingly supplemented with new methods. The level of evidence for treatment approaches has increased due to the development of systematic reviews and national and international recommendations.

AIM: To study the effectiveness of pneumokinetic micro-jet "needle-free" delivery of corticosteroid drug and fluorouracil in hypertrophic scars.

MATERIAL AND METHODS: We observed 23 patients (with hypertrophic scars. The average age was 31.3±4.3 years. The duration of the existence of hypertrophic scars in the average group was 7.8±2.3 months. Previously, patients did not receive therapy for the correction of scars. All patients were treated with intra-cicatricial administration of durant corticosteroid and fluorouracil. The technology of pneumokinetic micro-jet "needle-free" was used.

RESULTS: A high effect was achieved in all patients. Thus, the total Dermatological symptom scale index decreased with localization of the process on the face by 79.1% (p <0.01), with localization on the neck by 81.2% (p <0.01), with localization on the abdomen by 73.4% (p <0.01).

CONCLUSION: The technology of pneumokinetic micro-jet "needle-free" delivery of corticosteroid drug and fluorouracil subdermally can be considered as the method of choice in this category of patients.

Keywords

hypertrophic scars / laser therapy / glucocorticosteroids / fluorouracil

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RIGHTS & PERMISSIONS

Nogerov A.R., Kruglova L.S., Gryazeva N.V.