Fluctophoresis of mexidol following sinus lifting in the patents presenting with the chronic inflammatory processes in the maxillary sinus

Abstract

The authors describe the new method for the rehabilitation of the patents presenting with the chronic inflammatory processes of the maxillary sinus during the early postoperative period after classical and local sinus lifting with simultaneous implantation. The patients were treated with the use of the standard therapeutic modalities supplemented either by fluctophoresis of mexidol (the study group) or mexidol fluctuorization (control group). The study has demonstrated that a course of rehabilitative treatment resulted in the recovery of the nasal breathing function, relief of the pain syndrome, improvement of the draining function of the nasal cavity, and normalization of conduction in the second branch of the trigeminal nerve. Activation of the osteoregeneration processes was documented based on the results of determination of the levels of alkaline phosphatase and its isomer localized in the bone tissue. The results of microbiological investigations confirmed the difference between the compositions of the microflora in the nasal cavity in the cases of rhinogenic and odontogenic maxillary sinusitis after the surgical intervention on the alveolar process of the maxilla with simultaneous dental implantation. It was shown that fluctophoresis and fluctuorization of mexidol have a well-apparent rehabilitative potential. It was manifested as a significant reduction in the number of samples suggesting the absence of growth within 7 days after the application of both modalities. A similar effect was documented only 12-14 days after standard therapy. The long-term follow-up failed to reveal cases of rejection of the dental implant during two years after the operation. It is concluded that the introduction of mexidol fluctophoresis into the program of rehabilitative measures makes up a complementary and potentiating approach to be employed in the early postoperative period following sinus lifting in the patents presenting with rhinogenic and odontogenic maxillary sinusitis.

Keywords

fluctuorization / mexidol / dental implantation / sinus lifting / maxillary sinusitis

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