The experience with the use of combined therapy for postmenopausal women with low bone mineral density

Abstract

The objective of the present work was to study dynamics of the quality of life, indicators of phosphorus-calcium metabolism, markers of osteogenesis, bone resorption, and bone mineral density (BMD) in women of advanced age presenting with postmenopausal osteopenia during medicamental (sodium alendronate) and non-medicamental correction of bone metabolism during 6 months. The maximum improvement of the quality of life and bone mineral density was documented in the group of women given combined rehabilitative treatment. The positive osteogenic effect of whole body vibration appears to be due to the stimulation of the bone tissue formation processes manifest as the enhanced level of the osteogenic marker osteocalcin. This effect was lacking in the women treated with sodium alendronate alone.

Keywords

whole body vibration / osteopenia / antiresorptive therapy

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