Complex treatment of patients with hormone-dependent atrophic scars

Abstract

BACKGROUND: There are a large number of different methods of treating striae, starting with local therapy with various oils, ending with hardware techniques, but standardized treatment protocols have not yet been developed, which forces us to look for new promising combined treatment regimens

AIMS: To study the effectiveness of therapeutic complexes in patients with atrophic hormone-dependent scars.

MATERIAL AND METHODS: 145 patients with hormone-dependent scars with different AP phenotypes were followed up. In groups 1A and 1B, phototherapy was performed using broadband incoherent light-IPL therapy. In groups 2A and 2B, exposure was performed using bipolar fractional radiofrequency therapy. In groups 3A and 3B, the patient underwent a mesoroller microneedling procedure. PRP therapy was performed in groups 1B, 2B, and 3B. A visual analog scale (VAS) was used to evaluate the effectiveness.

RESULTS: Comparing the data obtained, it should be noted that, regardless of the age of the scar (red, white), the developed complex methods of therapy showed greater effectiveness than monotherapy with pulsed broadband light, RF microneedles or microneedling.

CONCLUSION: The combination of RF-therapy and PRP-therapy showed the greatest effectiveness against all clinical symptoms of AR, IPL-therapy with plasma with cells and plasma-with-cells microneedling showed a comparable high efficiency in different periods of AR existence.

Keywords

atrophic hormone-dependent scars / laser therapy / microneedle radiofrequency therapy / microneedling / autologous plasma with cells

References

[1] Thomas RG, Liston WA. Clinical associations of striae gravidarum. J Obstet Gynaecol. 2004;24(3):270–271. doi: 10.1080/014436104101001660779

[2] Thomas R.G., Liston W.A. Clinical associations of striae gravidarum // J Obstet Gynaecol. 2004. Vol. 24, N 3. P. 270–271. doi: 10.1080/014436104101001660779

[3] Yamaguchi K, Suganuma N, Ohashi K. Quality of life evaluation in Japanese pregnant women with striae gravidarum: a cross-sectional study. BMC Res Notes. 2012;5:450. doi: 10.1186/1756-0500-5-450

[4] Yamaguchi K., Suganuma N., Ohashi K. Quality of life evaluation in Japanese pregnant women with striae gravidarum: a cross-sectional study // BMC Res Notes. 2012. Vol. 5. P. 450. doi: 10.1186/1756-0500-5-450

[5] Atwal GS, Manku LK, Griffiths CE, Polson DW. Striae gravidarum in primiparae. Br J Dermatol. 2006;155(5):965–969. doi: 10.1111/j.1365-2133.2006.07427.x

[6] Atwal G.S., Manku L.K., Griffiths C.E., Polson D.W. Striae gravidarum in primiparae // Br J Dermatol. 2006. Vol. 155, N 5. P. 965–969. doi: 10.1111/j.1365-2133.2006.07427.x

[7] Watson RE. Stretching the point: an association between the occurrence of striae and pelvic relaxation? J Invest Dermatol. 2006;126(8):1688–1689. doi: 10.1038/sj.jid.5700316

[8] Watson R.E. Stretching the point: an association between the occurrence of striae and pelvic relaxation? // J Invest Dermatol. 2006. Vol. 126, N 8. P. 1688–1689. doi: 10.1038/sj.jid.5700316

[9] Khatri KA, Mahoney DL, McCartney MJ. Laser scar revision: a review. J Cosmet Laser Ther. 2011;13(2):54–62. doi: 10.3109/14764172.2011.564625

[10] Khatri K.A., Mahoney D.L., McCartney M.J. Laser scar revision: a review // J Cosmet Laser Ther. 2011. Vol. 13, N 2. P. 54–62. doi: 10.3109/14764172.2011.564625

[11] Brewin MP, Lister TS. Prevention or treatment of hypertrophic burn scarring: a review of when and how to treat with the pulsed dye laser. Burns. 2014;40(5):797–804. doi: 10.1016/j.burns.2013.12.017

[12] Brewin M.P., Lister T.S. Prevention or treatment of hypertrophic burn scarring: a review of when and how to treat with the pulsed dye laser // Burns. 2014. Vol. 40, N 5. P. 797–804. doi: 10.1016/j.burns.2013.12.017

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