The effect of electrical stimulation by bipolar-pulse microcurrents on regeneration processes in experiment and clinic

Abstract

Objective. The purpose of this study is to study the effect of electrical stimulation by bipolar-pulsed microcurrents: in an experiment on lymphatic drainage of a marker from the mesentery of mice and in the clinic on patients with hypertrophic scars in the face.

Materials and methods. In the experiment, the rate of resorption of the marker from the mesentery of mice (n = 10) receiving the “placebo” procedure and mice (n = 10) receiving the course of electrical stimulation with bipolar-pulsed microcurrents were measured under a light microscope. In addition, the clinic observed patients aged 18 to 60 years (n = 100), with hypertrophic scars in the face area that arose for various reasons. Of these, the 1st (control) group of patients (n = 10) received only one standard drug therapy, and the 2nd (main) group (n = 90) additionally received electrical stimulation with bipolar-pulsed microcurrents in the face area.

Results. The experiment showed that the rate of resolution of the marker in the mesentery of the intestines of mice after a course of electrical stimulation was greater than in mice treated with the placebo procedure. In a clinical study in patients in the 2nd (main) group after a course of electrical stimulation, on the background of drug therapy, better results were achieved on the Vancouver Scar Scale and in a shorter time period than in patients in the 1st (control) group who received drug therapy . The greater effectiveness of the results in patients in the 2nd (main) group was confirmed by the data of statistical regression analysis.

Conclusions. The results of this experiment showed that electrical stimulation by bipolar-pulsed microcurrents accelerates lymphatic drainage in the mesentery of the intestines of mice. In a clinical study, the use of electrical stimulation with bipolar-pulsed microcurrents in patients with hypertrophic scars in the face region in the 2nd group showed high efficiency and the transition of hypertrophic scars to normotrophic ones in earlier periods.

Keywords

electrical stimulation / microcurrents / lymphatic drainage / hypertrophic scars

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