Lipid metabolism disorders within chronic kidney disease in association with metabolic syndrome

Abstract

The distribution and predictors of chronic kidney disease associated with metabolic syndrome among outpatients investigated and treated in policlinic № 30 (Petrograd region, St. Petersburg) were studied. 1800 patients with cardiovascular pathology were investigated, among them 380 patients (205 or 53,9% females and 175 or 46,1 % males) with metabolic syndrome and microalbuminuria were selected. The middle age of the patients was 59,2±3,6 (43+73) years, arterial hypertension lasted 12,0+ 4,5 years. The chronic kidney disease was diagnosed according to decrease of glomerular filtration rate and microalbuminuria. The distribution of metabolic syndrome with microalbuminuria among all patients studied was 21,1%. In patients with metabolic syndrome and microalbuminuria, a level of lipid metabolism disorders was shown to grow higher and blood pressure was increased in accordance with reduction of kidney function, that elevated risk of cardiovascular complications.

Keywords

chronic kidney disease / metabolic syndrome / microalbuminuria / glomerular filtration rate / arterial hypertension / lipid metabolism

RIGHTS & PERMISSIONS

Tarakanovskaya T.A., Yunusov I.A.