Cytogenetic investigation of peripheral blood lymphocytes in Hodgkin's lymphomas

S N Kolubaeva; A V Novitsky; L V Myakoshina; N V Illyin; J N Vinogradova; V L Evtushenko; N A Viktorova; O P Krasnova; A A Titova

doi:10.17816/MAJ9347-51

Medical academic journal ›› 2009, Vol. 9 ›› Issue (3) : 47 -51. DOI: 10.17816/MAJ9347-51

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Cytogenetic investigation of peripheral blood lymphocytes in Hodgkin's lymphomas

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Abstract

Chromosomal injuries in 84 patients with Hodgkin's lymphoma were investigated by differential painting. Clonal aberrations were found in 22 patients and 61 patients had various nonclonal aberrations. Comparison of discovered injuries with the injuries published by others shows that the character of injuries and immunological status may depend on geographical regions where the patients live.The most frequent regions of chromosomal injuries were localized in the chromosomes 2.3,6,12, X.

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Hodgkin's lymphoma / chromosomal clonal and nonclonal injuries / stage of illness / peripheral blood lymphocytes

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S N Kolubaeva, A V Novitsky, L V Myakoshina, N V Illyin, J N Vinogradova, V L Evtushenko, N A Viktorova, O P Krasnova, A A Titova. Cytogenetic investigation of peripheral blood lymphocytes in Hodgkin's lymphomas. Medical academic journal, 2009, 9(3): 47-51 DOI:10.17816/MAJ9347-51