Perinatal infection caused by group B streptococcus (Streptococcus agalactie)

Abstract

Aim. The matter of presented paper addressed to medical workers with aim to give them modern information on the role of group В streptococcal (GBS) strains in pathology of pregnancy and in perinatal diseases. Basic contents. The review is given on present scientific literature and health care experience concerning leading role of GBS in pathology of pregnancy and newborns. Information is described on the mechanism of GBS carryership, their distribution in genital ways of women and men, ability to cause severe invasive neonatal diseases with high lethality and influence on development of embryo. It is obvious that infection diseases caused by GBS should be considered as infection transmitted through sexual contacts. The high expedience of prophylactic measures was underlined with the aim to diminish the indexes of perinatal morbidity and mortality. Some molecular and genetic subjects on GBS diagnostics and recombinant vaccine construction are discussed. Conclusion. The development of recommendations for prophylactic measures and national regulation scheme against GBS perinatal diseases was grounded.

Keywords

perinatal pathology / invasive infections / prophylactic measures / PCR diagnostics / recombinant vaccine

RIGHTS & PERMISSIONS

Totolian A.A.