The effect of the composition of leuzea and cranberry meal extracts on testosterone level in mice

Abstract

BACKGROUND: Current research suggests the potential use of natural components as sources of anabolic compounds. One of these is a new composition of leuzea and cranberry meal extracts, which, as was found earlier, exhibits a dose-dependent anabolic effect.

AIM: To establish the supposed mechanism of the anabolic effect in the composition of leuzea and cranberry meal extracts.

MATERIALS AND METHODS: In the experiment, CD-1 mice of both sexes weighing 20–25 g were used. All animals were measured blood testosterone concentration in dynamics: 0 point (before the administration of the analyzed compositions), 30, 60, 120, 180 minutes after administration.

RESULTS: After a single administration of the composition of leuzea and cranberry meal extracts at a dose of 70+500 mg/kg, the level of testosterone in the blood mice of both sexes increases, and the increase in testosterone levels in females is less pronounced than in males.

CONCLUSIONS: One of the supposed mechanisms of the anabolic effect in the composition, characterized by an increase in blood testosterone levels, has been established.

Keywords

testosterone / leuzea extract / cranberry meal / mice

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Khalikova D.A., Ankov S.V., Meshkova J.V., Tolstikova T.G.