On the history of the study of endogenous antibiotics

Abstract

The review presents data on the history of the discovery of the first endogenous antibiotic compounds, on the contribution of Russian scientists, in particular, researchers from the Institute of Experimental Medicine (St. Petersburg), in the study of the structural and functional properties of antimicrobial proteins and peptides – important molecular factors of innate immunity that can act as an alternative to conventional antibiotics in the fight to control pathogenic microorganisms.

Keywords

antimicrobial proteins and peptides / defensins / cathelicidins / innate immunity

References

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