Etiology of severe acute respiratory infections in Ekaterinburg in different epidemic seasons

Abstract

BACKGROUND: Acute respiratory viral infections are ubiquitous. Part of the cases are severe and require hospital treatment.

AIM: Studying the etiology of severe acute respiratory infections in patients of Ekaterinburg hospitals in different epidemic seasons (from 2017 to 2020).

MATERIALS AND METHODS: 1,132 cases of severe acute respiratory infection were assessed. The structure of laboratory-confirmed cases was determined.

RESULTS: In the assessed seasons, the proportion of respiratory viruses in the etiological structure of severe acute respiratory infections was 56.0% on average. B/Yamagata lineage of influenza viruses was predominant in the season of 2017/2018 (23.9% from the total number of respiratory viruses), — influenza А (H1N1)pdm09 viruses were predominant in the season of 2018/2019 (27.7%), and influenza A and B viruses were identified in 2019/2020 (39.4% and 31.7%, respectively).

СONCLUSIONS: The obtained results confirm a key role of influenza viruses in the etiology of severe acute respiratory infections among the hospital patients in different epidemic seasons.

Keywords

severe acute respiratory infections / etiology / influenza viruses / hospital

References

[1] Pisareva MM, Eder VA, Buzitskaya ZhV, et al. Etiological structure of influenza and other ARVI in St. Petersburg during epidemic seasons 2012–2016. Problems of Virology. 2018;63(5):233–239. (In Russ.) DOI: 10.18821/0507-4088-2018-63-5-233-239

[2] Писарева М.М., Едер В.А., Бузицкая Ж.В. и др. Этиологическая структура гриппа и других ОРВИ в Санкт-Петербурге в эпидемические сезоны 2012–2016 гг. // Вопросы вирусологии. 2018. Т. 63, № 5. С. 233–239. DOI: 10.18821/0507-4088-2018-63-5-233-239

[3] Svistunova NV, Baranova IP, Zykova OA, Fedorova OV. A comparative analysis of clinical specificities of influenza A(H1N1) and influenza в in hospitalized patients. Infectious Diseases. 2013;11(1):27–32. (In Russ.)

[4] Свистунова Н.В., Баранова И.П., Зыкова О.А., Федорова О.В. Сравнительный анализ клинических особенностей гриппа А(Н1N1) и гриппа В у госпитализированных больных // Инфекционные болезни. 2013. Т. 11, № 1. С. 27–32.

[5] Svyatchenko SV, Durymanov AG, Susloparov IM, et al. Severe cases of seasonal influenza in Russia in 2015–2016 and 2016–2017. Journal of Microbiology, Epidemiology Immunobiology. 2018;(1):32–39. (In Russ.) DOI: 10.36233/0372-9311-2018-1-32-39

[6] Святченко C.B., Дурыманов А.Г., Суслопаров И.М. и др. Тяжелые случаи заболевания гриппом на территории Российской Федерации в течение эпидемических сезонов 2015–2016 и 2016–2017 // Журнал микробиологии, эпидемиологии и иммунобиологии. 2018. № 1. С. 32–39. DOI: 10.36233/0372-9311-2018-1-32-39

[7] Meerhoff T, Simaku A, Ulqinaku D, et al. Surveillance for severe acute respiratory infections (SARI) in hospitals in the WHO European region – an exploratory analysis of risk factors for a severe outcome in influenza-positive SARI cases. BMC Infect Dis. 2015;15:1. DOI: 10.1186/s12879-014-0722-x

[8] Meerhoff T.J., Simaku A., Ulqinaku D. et al. Surveillance for severe acute respiratory infections (SARI) in hospitals in the WHO European region – an exploratory analysis of risk factors for a severe outcome in influenza-positive SARI cases // BMC Infect. Dis. 2015. Vol. 15. P. 1. DOI: 10.1186/s12879-014-0722-x

[9] Rukovodstvo Evropeiskogo regional’nogo byuro VOZ po dozornomu ehpidnadzoru za grippom sredi lyudei [Internet]. WHO. 2011. (In Russ.) Available from: http://www.euro.who.int/data/assets/pdffile/0003/90444/e92738R.pdf. Accessed: 07.03.2021.

[10] Руководство Европейского регионального бюро ВОЗ по дозорному эпиднадзору за гриппом среди людей [электронный ресурс] // ВОЗ. 2011. Режим доступа: http://www.euro.who.int/data/assets/pdffile/0003/90444/e92738R.pdf. Дата обращения: 07.03.2021.

RIGHTS & PERMISSIONS

Lelenkova E.V., Markaryan A.Y.