HIV infection, secondary conditions and comorbidities. Part 2. Concomitant diseases

Vadim V. Rassokhin; Olga N. Leonova; Ekaterina V. Boeva; Elena V. Stepanova; Nikolay A. Belyakov; Ralph J. DiClemente

doi:10.17816/MAJ1915-16

Medical academic journal ›› 2019, Vol. 19 ›› Issue (1) : 5 -16. DOI: 10.17816/MAJ1915-16

Analytical reviews

research-article

HIV infection, secondary conditions and comorbidities. Part 2. Concomitant diseases

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Pavlov First Saint Petersburg State Medical University

Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology

Institute of Experimental Medicine

Saint Petersburg Centre for Prevention and Control of AIDS and Infectious Diseases

Department of Epidemiology College of Global Public Health New York University

MD, PhD, Professor of the Department of Socially Significant Infections; Leading Research Associate; Head of the Laboratory of Chronic Viral Infections, Department of Ecological Physiology

MD, PhD, Associate Professor of the Department of Socially Significant Infections; Head of the Saint Petersburg Center for Prevention and Control of AIDS and Infectious Diseases

Assistant of the Department of Socially Significant Infections; Head of the Department of Chronic Viral Infection

Professor, Department of Socially Significant Infections; MD, PhD, Deputy Chief Medical Officer

MD, PhD, Professor, Academician of the Russian Academy of Sciences, Head of the Department of Socially Significant Infections; Head of the North-Western District AIDS Prevention and Control Center; Chief Research Worker

MD, PhD, Professor, Chair of the Department of Social and Behavioral Sciences; Professor, Department of Epidemiology

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Abstract

Comorbid conditions are typical for many chronic pathological processes, especially at a mature and old age. For several reasons, a special place in the formation of these conditions takes HIV infection in combination with non-communicable diseases. The general characteristics of the secondary athologies, which remain one of the leading causes of severe complications and mortality, are presented. Particular attention is focused on possible concomitant somatic pathology, which may affect the quality of life and the prognosis. Among pathological precosses are lesions of the gastrointestinal and urinary tracts, cardiovascular diseases and malignant neoplasms. A method for the integrated assessment of the severity of a patient’s condition with a combination of comorbidity and HIV infection is presented. This method allows to improve the prediction of the course and outcome of the main and associated diseases, as well as to influence the nature of the diagnostic and therapeutic processes.

Keywords

HIV infection / comorbidities / concomitant diseases / integral assessment of severity

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Vadim V. Rassokhin, Olga N. Leonova, Ekaterina V. Boeva, Elena V. Stepanova, Nikolay A. Belyakov, Ralph J. DiClemente. HIV infection, secondary conditions and comorbidities. Part 2. Concomitant diseases. Medical academic journal, 2019, 19(1): 5-16 DOI:10.17816/MAJ1915-16

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