Functional activity of peripheral blood monocytes after mechanical trauma
S F Bagnenko , L P Pivovarova , E G Rybakina , M E Malyshev , O B Ariskina , I V Osipova , A E Chikin , S N Shanin , I A Kozinets , O D Chesnokov , E A Korneva
Medical academic journal ›› 2010, Vol. 10 ›› Issue (1) : 64 -72.
Functional activity of peripheral blood monocytes after mechanical trauma
The results of studying functional activity of peripheral blood monocytes in patients after severe multitrauma have been represented. It was shown that in early period of traumatic disease peripheral blood monocytes of patients saved both regulatory functions (lymphocyte activating factors production) and effectory functions, but the reserves of their activation and proliferation are the lower the more severe are the injury and the shock. It appears thatT-lymphocytopenia, monocytopenia and increased oxidative activity of peripheral blood monocytes can be employed as prognostic criteria for the progression of severe purulent complications and sepsis in patients with mechanical multitrauma.
trauma / monocytes / purulent complications / sepsis
Bagnenko S.F., Pivovarova L.P., Rybakina E.G., Malyshev M.E., Ariskina O.B., Osipova I.V., Chikin A.E., Shanin S.N., Kozinets I.A., Chesnokov O.D., Korneva E.A.
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