Erythema Infectiosum: clinical case
Albina G. Pashinyan , N. K Runikhina , E. Yu Mokeeva
Russian Journal of Skin and Venereal Diseases ›› 2016, Vol. 19 ›› Issue (4) : 206 -209.
Erythema Infectiosum: clinical case
Human Parvovirus B19 has been recognized as the causative agent of a wide range of diseases. The cellular receptorfor parvovirus B19 is P antigen located on the trophoblast cells, bone marrow, liver, kidney, synovium, etc. has been associated with many clinical situations, erythema infectiosum and erythroblastopenia crisis. In the absence of P-antigen, revealed no susceptibility to parvovirus infection. Infection in pregnant women under 20 weeks gestation can lead to miscarriage or non-immune hydrops, fetal death. 1-5% of women are susceptible to parvovirus infection during pregnancy. Viral infection may be responsible for aplastic anaemia in immuno-compromised patients. Diagnosis ofparvovirus infection B19 is based on the results of general blood analysis; biochemical analysis of blood; serological methods, PCR detection of IgM, immunoblot IgM/IgG. The most common clinicalform of parvovirus B19 infection in children is erythema infectiosum. It is also called “fifth disease”. Erythema infectiosum is characterized by a viral prodrome followed by the “slapped cheek’ facial rash and macula papular lace or mesh rash on the skin of the trunk and extensor surfaces.
infectious erythema / “fifth disease” / parvovirus B19 / diagnosis methods
Eco-Vector
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