Phenotypic variability of Trichomonas vaginalis as the cause of resistance to metronidazole
Natalie I. Syuch , K. E Machkalyan , N. V Makhneva
Russian Journal of Skin and Venereal Diseases ›› 2016, Vol. 19 ›› Issue (1) : 64 -68.
Phenotypic variability of Trichomonas vaginalis as the cause of resistance to metronidazole
The results of the study of the nitrosoguanidine mutagen effect on phenotypic variability of Trichomonas vaginalis are presented. Formation of non flagellated protozoa is detected. The relationship between torpid and difficult to treat forms of urogenital trichomoniasis with the presence of amastigote (non flagellated) forms with simple changes in the genome that have a high potential for survival is described.
Trichomonas vaginalis / mutation / non flagellated form / resistance to metronidazole
Eco-Vector
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