Diagnosis of specific hepatitis in patients with lepra

O A Mesnyankina; O V Degtyarev; V Z Naumov; V V Duyko; O A Mesnyankina; O V Degtyarev; V Z Naumov; V V Duyko

doi:10.17816/dv37380

Russian Journal of Skin and Venereal Diseases ›› 2011, Vol. 14 ›› Issue (6) : 38 -41. DOI: 10.17816/dv37380

Articles

other

Diagnosis of specific hepatitis in patients with lepra

Author information +

History +

PDF

Abstract

Among the most prevalent visceral complications of leprous process is chronic leprous hepatitis, the main etiological factor of which is persisting Mycobacterium leprae (M. leprae) in tissues of affected organ. It was shown that evaluation of α1-antitripsin, α2-macroglobulin, gaptoglobin and α1-acidic glicoproteine in patients with lepra has important diagnostic and prognostic value: in a combination with other parameters it helps to reveal liver involvement; in a combination with enzyme-immunoassay detection of antibodies to M. Leprae antigens allows to reveal latent persistency of aetiologic agent; reflects the disease severity; allows to predict the course of the most prevalent complication of lepra; and serves as a criterion of therapy efficacy.

Keywords

lepra / liver / α1-antitripsin / α1-acidic glicoproteine / α2-macroglobulin / gaptoglobin

Cite this article

Download citation ▾

O A Mesnyankina, O V Degtyarev, V Z Naumov, V V Duyko, O A Mesnyankina, O V Degtyarev, V Z Naumov, V V Duyko. Diagnosis of specific hepatitis in patients with lepra. Russian Journal of Skin and Venereal Diseases, 2011, 14(6): 38-41 DOI:10.17816/dv37380

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Воллер А., Бидуэлл Д., Бартлет А. // Бюл. ВОЗ. - 1977. - Т. 53, № 1. - С. 38-48.

[2]	Дегтярёв О. В. Иммуноэпидемиологический контроль в условиях спорадической заболеваемости лепрой: Автореф. дис. ... канд. мед. наук. - М., 1998.

[3]	Дегтярёв О. В. Новые диагностические алгоритмы активности лепрозного процесса и мониторинг эффективности лечения больных лепрой в амбулаторных условиях: Автореф. дис. ... д-ра мед. наук. - М., 2006.

[4]	Делекторская Л. Н., Пименова Л. М., Кадашева О. Г. // Клин. лаб. диагн. - 1992. - № 1-2. - С. 49-58.

[5]	Дячина М. Н., Дегтярёв О. В., Васильев А. Э. Способ определения M. leprae у больных с регресом заболевания: Пат. РФ № 2137137 // Открытия. Изобретения.- 1999. - № 25. - С. 137.