Clinical immunological aspects of lichen planus development

Vladislav Yu. Udzhukhu; N. G Korotky; E. S Vasilyeva; A. A Kubylinsky; M. I Shemshuk; A. S Medvedeva

doi:10.17816/dv36925

Russian Journal of Skin and Venereal Diseases ›› 2015, Vol. 18 ›› Issue (1) : 18 -21. DOI: 10.17816/dv36925

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Clinical immunological aspects of lichen planus development

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Abstract

The clinical course of lichen planus (LP) was studied and the contribution of disorders in interleukine-dependent modulation of congenital and acquired immune response to the development of this dermatosis was evaluated. Twenty-eight patients with clinical variants of LP were observed. Differences in the clinical picture of LP in comparison with the classical descriptions were detected and disproportions in the system of interleukines, interferons, and some adhesion molecules were evaluated. Herpes simplex virus was found to be one of the factors triggering the development of LP.

Keywords

lichen planus / immune homeostasis / interleukines / interferons / adhesion molecules

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Vladislav Yu. Udzhukhu, N. G Korotky, E. S Vasilyeva, A. A Kubylinsky, M. I Shemshuk, A. S Medvedeva. Clinical immunological aspects of lichen planus development. Russian Journal of Skin and Venereal Diseases, 2015, 18(1): 18-21 DOI:10.17816/dv36925

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