Modern concepts of the epigenetic mechanisms of atopic dermatitis formation
L. N Kayumova , - Sami Baker , S. A Bruskin , L. G Garanyan , Nikolay G. Kochergin , O. Yu Olisova
Russian Journal of Skin and Venereal Diseases ›› 2014, Vol. 17 ›› Issue (4) : 42 -50.
Modern concepts of the epigenetic mechanisms of atopic dermatitis formation
Gene expression in atopic dermatitis was analyzed and the epigenetic profiles (DNA methylation status) of biopsy specimens from normal subjects and patients with atopic dermatitis before therapy were studied by the Illumina microchips in order to detect the key components of the pathological process. The results suggested more rational therapeutic approaches with consideration for the results of individual epigenetic testing.
DNA methylation / epigenetics / atopic dermatitis
Eco-Vector
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