Merkel cell carcinoma in psoriasis vulgaris
O. V Pravdina , V. A Vodolazskiy , A. S Reznikov , Vitaliy A. Okhlopkov
Russian Journal of Skin and Venereal Diseases ›› 2014, Vol. 17 ›› Issue (4) : 4 -7.
Merkel cell carcinoma in psoriasis vulgaris
Merkel cell carcinoma is a rare cutaneous tumor developing in sometimes in patients with psoriasis. The causes of this phenomenon are still unclear. In our case Merkel cell carcinoma has developed in a patient with severe psoriasis vulgaris. The clinical diagnosis of this tumor is extremely difficult. The tumor had to be differentiated from melanoma, basal cell carcinoma, squamous cell cutaneous carcinoma, and cutaneous lymphoma. The process was verified by immunohistochemical analysis with various immunohistochemical markers. Merkel cell carcinoma expressed neuroendocrine and epidermal markers.
Merkel cell carcinoma / psoriasis vulgaris / immunohistochemistry / skin tumors
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