Once more about hyperpigmentation
O. Yu Olisova , E. V Andreeva
Russian Journal of Skin and Venereal Diseases ›› 2014, Vol. 17 ›› Issue (2) : 20 -24.
Once more about hyperpigmentation
The efficiency and safety of Neoton serum and cream in therapy of hyperpigmentation of different origin were evaluated. A total of 20 women of 25-74 years of age with hyperpigmentation of different etiology were treated by neoton preparations (neoton cream in the morning and neoton serum at night). 12 patients presented with chloasma, 5 with postinflammatory hyperpigmentation, 2 with freckles, and 1 with photophytodermatitis. Therapy was continued for 3 months. Melanin levels in the foci were measured before, during, and after therapy by the Multi Skin Test Center MC 750 system (Germany). The foci regressed completely after 1 month of neoton therapy in 33% patients, significant improvement was attained during this period in 40%, and improvement in 27% of patients. Clinical recovery was attained after complete course (3 months) in 47%, significant improvement in 53% patients. The reduction of melatonin level served as an objective evidence of the treatment efficiency. Before therapy its levels were 90-125 arb. units (vs. 6-40 arb. units in normal skin), after 1 month of therapy melatonin levels reduced to 30-70 arb. units, and the levels after a complete course of 3 months were 15-55 arb. units. Only one patient developed a side effect (desquamation) which spontaneously regressed within several days. Neoton serum and cream were well tolerated and proved to be effective means for therapy of hyperpigmentations of different etiology.
melanin / hyperpigmentation / Neoton Radians cream / Neoton serum
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