Clinical observation of Muir-Tor-rais's syndrome
V. A Molochkov , Zh. S Kuntsevich , S. D Dibirova , Yu. V Molochkova , K. V Kazantseva
Russian Journal of Skin and Venereal Diseases ›› 2014, Vol. 17 ›› Issue (3) : 9 -11.
Clinical observation of Muir-Tor-rais's syndrome
Muir-Torrais ’ syndrome in a 60-year-old patient with a history of rectal adenocarcinoma and papillary cancer of the renal pelvis is described. The syndrome included corneal keratoacanthoma, sebaceous gland adenoma, and rectal adenocarcinoma. Keratoacanthoma was cured by peritumor injections of reaferon (interferon-a2b, 1.5 • 10 6 U every other day, 9 injections per course). Rectal cancer, diagnosed at the early stage, was effectively treated by surgery. During the subsequent 2 years the patient developed gastric cancer, which was also treated surgically with good results. The favorable course (without metastases) of visceral cancer in Muir-Torrais’s syndrome and the importance of detecting tumors of the sebaceous glands in patients with keratoacanthoma are emphasized.
Muir-Torrais’s syndrome / corneal keratoacanthoma / adenoma of sebaceous glands / rectal adenocarcinoma / reaferon
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