CD45 IN CUTANEOUS MELANOMA CELLS AS A MANIFESTATION OF TUMOR ATYPIA
M. B Aksenenko , L. A Shestakova , T. G Ruksha
Russian Journal of Skin and Venereal Diseases ›› 2013, Vol. 16 ›› Issue (4) : 6 -8.
CD45 IN CUTANEOUS MELANOMA CELLS AS A MANIFESTATION OF TUMOR ATYPIA
The expression of CD45 (hemopoietic cell marker) in cutaneous melanoma cells was studied in 96 patients (40 men and 56 women). The expression was detected in 17.5% patients, mainly with Clark’s tumor invasion levels IV and V and Breslow’s thickness of the tumor 3.7±1.09 mm. Data on the relationship between this marker’s expression and clinical morphological characteristics of the disease are presented. The differential diagnosis of cutaneous melanoma is discussed.
CD45 / cutaneous melanoma / CD45 / necrotization
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