CONTRIBUTION OF TOLL-LIKE RECEPTORS (TLR) — CONGENITAL IMMUNITY STIMULANTS — TO THE PATHOGENESIS OF SOME DERMATOSES

Abstract

The functions of Toll-like receptors (TLR) in the skin and their contribution to stimulation of congenital immunity in some chronic dermatoses caused by or complicated by bacterial, viral, or fungal infections are reviewed.

Keywords

congenital immunity / Toll-like receptors (TLR) / TLR-2 regul complex / therapy / seborrheic dermatitis / atopic dermatitis / acne

References

[1] Boasen J., Chisholm D., Lebet L. et al. // J. Allergy Clin. Immunol. — 2005. — Vol. 116, N 1. — P. 185—195.

[2] Curry J.L., Qin J.Z., Bonish B. et al. // Arch. Pathol. Lab. Med. — 2003. — Vol. 127. — P. 178—186.

[3] Heine H., Lien E. // Int. Arch. Allergy Immunol. — 2003. — Vol. 130, N 3. — P. 180—192.

[4] Ionescu M.A. // V Санкт-Петербургские дерматологические чтения, 3 октября 2011, Санкт-Петербург, www.dermatology.ru

[5] Ionescu M.A., Baroni A. S., Brambilla L.E. // G. Ital. Dermatol. Venereol. — 2011. — Vol. 146, N 3. — P. 185—189.

[6] Janeway C.A.Jr. // Cold Spring Harb. Symp. Quant. Biol. — 1989. — Vol. 54, Pt 1. — P. 1—13.

[7] Lemaitre B., Nicolas E., Michaut L. et al. // Cell. — 1996. — Vol. 86, N 6. — P. 973—983.

[8] Medzhitov R., Preston-Hurlburt P., Janeway C.A.Jr. // Nature. — 1997. — Vol. 388, N 6640. — P. 394—397.

[9] Pivarcsi A., Bodai L., Reth B. et al. // Int. Immun. — 2003. — Vol. 15. — P. 721—730.

[10] Poltorak A., He X., Smirnova I. et al. // Science. — 1998. — Vol. 282, N 5396. — P. 2085—2088.

[11] Tsuji R.F., Hoshino K., Noro Y. et al. // Clin. Exp. Allergy. — 2003. — Vol. 33, N 2. — P. 249—258.

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