Biochemical blood parameters correlating with severity of atopic dermatitis

A O Ol'shamovskaya; A V Babkin; R A Grashin; V V Barbinov; А О Olshamovskaya; А V Babkin; R А Grashin; V V Barbinov

doi:10.17816/dv36654

Russian Journal of Skin and Venereal Diseases ›› 2012, Vol. 15 ›› Issue (1) : 35 -38. DOI: 10.17816/dv36654

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Biochemical blood parameters correlating with severity of atopic dermatitis

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Abstract

139 patients with atopic dermatitis of different severity were examined. Based on SCORAD index patients were divided into 3 groups and a control group. In all patients level of immunoglobulin E in blood, concentration of eosinophils in peripherical blood and basic biochemical blood rates were studied. Changes of biochemical blood parameters were detected in 63% of patients with atopic dermatitis, indicating the synthetic and detoxification liver dysfunction. Inversely proportional correlation between blood urea concentration, cholesterol, gamma glutamine transferase and the severity of atopic dermatitis was revealed. Direct relationship between the level of immunoglobulin E and high SCORAD indexes was also confirmed.

Keywords

atopic dermatitis / index SCORAD / IgE / urea / cholesterol / gamma glutamine transferase

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A O Ol'shamovskaya, A V Babkin, R A Grashin, V V Barbinov, А О Olshamovskaya, А V Babkin, R А Grashin, V V Barbinov. Biochemical blood parameters correlating with severity of atopic dermatitis. Russian Journal of Skin and Venereal Diseases, 2012, 15(1): 35-38 DOI:10.17816/dv36654

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